Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
29465
CAS Number:
1060769-47-2
(S)-Fmoc-2-amino-5-(N'-Pbf-N''-trifluoroethyl-guanidino)-pentanoic acid
Purity:
≥ 95% (HPLC)
Synonym(s):
Fmoc-L-Arg(CF3CH2)(Pbf)-OH
Documents
$70.50 /5MG
Pack Size Availability Price
Request Bulk Quote
Product Information

(S)-Fmoc-2-amino-5-(N'-Pbf-N''-trifluoroethyl-guanidino)-pentanoic acid is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a protective Fmoc group, which facilitates the selective coupling of amino acids in solid-phase peptide synthesis, making it an essential tool for researchers in the field of medicinal chemistry. Its unique trifluoroethyl guanidino moiety enhances solubility and stability, allowing for more efficient synthesis of complex peptides and proteins.

This compound is particularly valuable in the development of therapeutics targeting various biological pathways, including those involved in cancer and metabolic disorders. Researchers appreciate its ability to improve the pharmacokinetic properties of peptide-based drugs, thereby increasing their efficacy and reducing potential side effects. With its robust performance in peptide synthesis and drug formulation, (S)-Fmoc-2-amino-5-(N'-Pbf-N''-trifluoroethyl-guanidino)-pentanoic acid stands out as a critical component for professionals aiming to innovate in the pharmaceutical industry.

Synonyms
Fmoc-L-Arg(CF3CH2)(Pbf)-OH
CAS Number
1060769-47-2
Purity
≥ 95% (HPLC)
Molecular Formula
C36H41F3N4O7S
Molecular Weight
730.8
MDL Number
MFCD18782822
Appearance
White solid
Optical Rotation
[a]D20 = -5 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Arg(CF3CH2)(Pbf)-OH
CAS Number
1060769-47-2
Purity
≥ 95% (HPLC)
Molecular Formula
C36H41F3N4O7S
Molecular Weight
730.8
MDL Number
MFCD18782822
Appearance
White solid
Optical Rotation
[a]D20 = -5 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-Fmoc-2-amino-5-(N'-Pbf-N''-trifluoroethyl-guanidino)-pentanoic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enabling researchers to create complex peptide sequences efficiently.
  • Drug Development: It plays a crucial role in the development of novel therapeutic agents, especially in the design of peptide-based drugs that target specific biological pathways.
  • Bioconjugation: The chemical is used in bioconjugation processes, allowing for the attachment of peptides to various biomolecules, which is essential in creating targeted drug delivery systems.
  • Research in Neuroscience: This compound is valuable in neuroscience research for studying receptor interactions and signaling pathways, aiding in the understanding of neurological disorders.
  • Protein Engineering: It is utilized in protein engineering to modify proteins for enhanced stability and functionality, which is important in various biotechnological applications.

Citations