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Catalog Number:
29343
CAS Number:
1310048-95-3
2-(3-Fluorobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity:
≥ 95% (HPLC)
Synonym(s):
3-Fluorophenylmethylboronic acid pinacol ester
Documents
$100.05 /100MG
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Product Information

2-(3-Fluorobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a versatile boron-containing compound that has garnered attention in various fields, particularly in organic synthesis and medicinal chemistry. This compound, also known as 3-Fluorobenzylboronic ester, is characterized by its unique dioxaborolane structure, which enhances its reactivity and stability in chemical reactions. Its ability to participate in Suzuki-Miyaura cross-coupling reactions makes it an invaluable tool for researchers looking to synthesize complex organic molecules, including pharmaceuticals and agrochemicals.

Moreover, the presence of the fluorobenzyl group in its structure allows for fine-tuning of electronic properties, making it suitable for applications in the development of novel materials and drug candidates. Its high selectivity and efficiency in coupling reactions provide significant advantages over traditional boronic acids, enabling chemists to achieve higher yields with fewer by-products. This compound is particularly beneficial for those in the pharmaceutical industry seeking to streamline their synthesis processes while maintaining high standards of purity and efficacy.

Synonyms
3-Fluorophenylmethylboronic acid pinacol ester
CAS Number
1310048-95-3
Purity
≥ 95% (HPLC)
Molecular Formula
C13H18BFO2
Molecular Weight
236.09
MDL Number
MFCD10698518
PubChem ID
71306021
Appearance
Colorless to dark yellow liquid
Conditions
Store at 0-8 °C
General Information
Synonyms
3-Fluorophenylmethylboronic acid pinacol ester
CAS Number
1310048-95-3
Purity
≥ 95% (HPLC)
Molecular Formula
C13H18BFO2
Molecular Weight
236.09
MDL Number
MFCD10698518
PubChem ID
71306021
Appearance
Colorless to dark yellow liquid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-(3-Fluorobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of targeted therapies for cancer treatment.
  • Organic Synthesis: It is used in organic chemistry for the formation of boron-containing compounds, which are essential in creating complex organic molecules.
  • Material Science: The compound is applied in the development of advanced materials, such as polymers and coatings, enhancing their properties through boron chemistry.
  • Fluorescent Probes: It is utilized in the creation of fluorescent probes for biological imaging, allowing researchers to track cellular processes with high precision.
  • Environmental Chemistry: The compound plays a role in environmental applications, such as the development of sensors for detecting pollutants, thereby contributing to sustainability efforts.

Citations