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Catalog Number:
29323
CAS Number:
102971-73-3
R-Fmoc-2-amino-3-(3-tert-butoxycarbonyl-propylsulfanyl)propionic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Cys(tert-butoxycarbonylpropyl)-OH
Documents
$72.31 /100MG
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Product Information

(R)-Fmoc-2-amino-3-(3-tert-butoxycarbonyl-propylsulfanyl)propionic acid is a versatile amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, which includes a tert-butoxycarbonyl group and a sulfanyl side chain, enhances its stability and solubility, making it an ideal choice for researchers focused on developing complex peptide sequences.

In practical applications, (R)-Fmoc-2-amino-3-(3-tert-butoxycarbonyl-propylsulfanyl)propionic acid serves as a key building block in the production of bioactive peptides, pharmaceuticals, and therapeutic agents. Its ability to facilitate the formation of disulfide bonds and its compatibility with various coupling reagents make it particularly valuable in the synthesis of cyclic peptides and other advanced biomolecules. Researchers and industry professionals can leverage this compound to streamline their synthesis processes and enhance the efficacy of their peptide-based products.

Synonyms
Fmoc-L-Cys(tert-butoxycarbonylpropyl)-OH
CAS Number
102971-73-3
Purity
≥ 98% (HPLC)
Molecular Formula
C26H31NO6S
Molecular Weight
485.6
MDL Number
MFCD11226818
PubChem ID
77702801
Melting Point
88 - 95 °C
Appearance
White powder
Optical Rotation
[a]D20 = -30 ± 2 º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Cys(tert-butoxycarbonylpropyl)-OH
CAS Number
102971-73-3
Purity
≥ 98% (HPLC)
Molecular Formula
C26H31NO6S
Molecular Weight
485.6
MDL Number
MFCD11226818
PubChem ID
77702801
Melting Point
88 - 95 °C
Appearance
White powder
Optical Rotation
[a]D20 = -30 ± 2 º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-Fmoc-2-amino-3-(3-tert-butoxycarbonyl-propylsulfanyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without affecting other functional groups.
  • Drug Development: Its unique structure aids in the design of novel peptides and peptidomimetics, which can lead to the development of new therapeutic agents in pharmaceuticals.
  • Bioconjugation: The compound can be used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Research in Protein Engineering: It plays a significant role in protein engineering, where its properties help in modifying proteins for enhanced stability and activity, benefiting fields like biotechnology.
  • Analytical Chemistry: This chemical is also employed in analytical techniques for the characterization of complex mixtures, providing insights into molecular interactions and structures.

Citations