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Catalog Number:
29031
CAS Number:
203854-59-5
Fmoc-(S-2-(aminomethyl)-3-methylbutanoic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
(S-Fmoc-2-aminomethyl-3-methyl-butyric acid, (S-Fmoc-β2-homovaline
Documents
$234.85 /25MG
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Product Information

Fmoc-(S)-2-(aminomethyl)-3-methylbutanoic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers and professionals in the fields of medicinal chemistry and biochemistry. The compound's chirality enhances its relevance in the synthesis of enantiomerically pure compounds, which is crucial for the development of pharmaceuticals with specific biological activity.

In addition to its role in peptide synthesis, Fmoc-(S)-2-(aminomethyl)-3-methylbutanoic acid can be employed in the preparation of various bioactive molecules, contributing to advancements in drug discovery and development. Its stability and compatibility with various coupling reagents make it a preferred choice for chemists looking to streamline their synthetic processes. This compound not only facilitates the creation of complex peptide sequences but also supports the development of targeted therapies, showcasing its significant potential in modern pharmaceutical applications.

Synonyms
(S-Fmoc-2-aminomethyl-3-methyl-butyric acid, (S-Fmoc-β2-homovaline
CAS Number
203854-59-5
Purity
≥ 99% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.42
MDL Number
MFCD07372881
PubChem ID
53397703
Appearance
White powder
Optical Rotation
[a]D20 = +21 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
(S-Fmoc-2-aminomethyl-3-methyl-butyric acid, (S-Fmoc-β2-homovaline
CAS Number
203854-59-5
Purity
≥ 99% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.42
MDL Number
MFCD07372881
PubChem ID
53397703
Appearance
White powder
Optical Rotation
[a]D20 = +21 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-2-(aminomethyl)-3-methylbutanoic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without affecting other functional groups.
  • Drug Development: It is employed in the design of peptide-based drugs, enhancing the stability and bioavailability of therapeutic peptides, which is crucial in pharmaceutical formulations.
  • Bioconjugation: The chemical is used in bioconjugation processes to attach peptides to other biomolecules, facilitating the development of targeted drug delivery systems.
  • Research in Neuroscience: It aids in the synthesis of neuropeptides, which are important for understanding neurological functions and developing treatments for neurological disorders.
  • Custom Peptide Libraries: Researchers utilize this compound to create diverse peptide libraries for screening potential drug candidates, accelerating the discovery of new therapeutics.

Citations