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Catalog Number:
28757
CAS Number:
222166-38-3
Fmoc-1-amino-1-cyclooctanecarboxylic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-acoc-OH
Documents
$72.31 /100MG
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Product Information

Fmoc-1-amino-1-cyclooctanecarboxylic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential tool for chemists working in the field of medicinal chemistry. Its unique cyclooctane structure provides enhanced conformational flexibility, which can be beneficial in designing peptides with specific biological activities.

Researchers appreciate Fmoc-1-amino-1-cyclooctanecarboxylic acid for its ability to facilitate the creation of complex peptide sequences while maintaining stability under various reaction conditions. This compound is particularly relevant in the development of peptide-based therapeutics and can be employed in the synthesis of cyclic peptides, which often exhibit improved potency and selectivity. Its application in combinatorial chemistry also opens avenues for high-throughput screening of potential drug candidates, making it a valuable asset in pharmaceutical research and development.

Synonyms
Fmoc-acoc-OH
CAS Number
222166-38-3
Purity
≥ 98% (HPLC)
Molecular Formula
C24H27NO4
Molecular Weight
393.48
MDL Number
MFCD03426230
PubChem ID
1512632
Appearance
White powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-acoc-OH
CAS Number
222166-38-3
Purity
≥ 98% (HPLC)
Molecular Formula
C24H27NO4
Molecular Weight
393.48
MDL Number
MFCD03426230
PubChem ID
1512632
Appearance
White powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-1-amino-1-cyclooctanecarboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for amino acids in solid-phase peptide synthesis, enhancing the efficiency and selectivity of the process.
  • Drug Development: Its unique structure allows for the design of cyclic peptides, which can lead to more stable and effective drug candidates in pharmaceutical research.
  • Bioconjugation: The compound can be used to create bioconjugates, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in diagnostics and therapeutics.
  • Material Science: It plays a role in the development of new materials, particularly in creating polymers with specific properties for applications in coatings and adhesives.
  • Research in Neuroscience: The compound's structure is beneficial in studying receptor interactions, aiding in the understanding of neurological pathways and potential treatments for neurological disorders.

Citations