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Catalog Number:
28510
CAS Number:
59045-82-8
S-(+)-Nipecotic acid
Purity:
≥ 99% (Titration)
Synonym(s):
(S-(+)-3-Piperidinecarboxylic acid
Documents
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Product Information

(S)-(+)-nipecotic acid is a chiral compound known for its significant role in the field of neuroscience and pharmacology. This compound, also referred to as (S)-nipecotic acid, is a derivative of piperidine and is recognized for its ability to act as a GABA uptake inhibitor. Its unique properties make it a valuable tool in research focused on neurological disorders, particularly in studies related to anxiety, epilepsy, and other conditions influenced by GABAergic signaling.

Researchers and industry professionals utilize (S)-(+)-nipecotic acid to explore its potential therapeutic applications, including its role in enhancing GABAergic neurotransmission, which can lead to the development of novel treatments for various neurological conditions. Its chiral nature allows for targeted interactions within biological systems, making it a preferred choice in the synthesis of pharmaceuticals aimed at modulating GABA levels. With its promising applications in drug development and neuropharmacology, (S)-(+)-nipecotic acid stands out as a compound of interest for advancing therapeutic strategies in mental health and neurological research.

Synonyms
(S-(+)-3-Piperidinecarboxylic acid
CAS Number
59045-82-8
Purity
≥ 99% (Titration)
Molecular Formula
C6H11NO2
Molecular Weight
129.16
MDL Number
MFCD01630807
PubChem ID
4498
Melting Point
253-254 °C (dec.)
Appearance
White off-white powder
Optical Rotation
[a]D20 = +5 ± 1.5º (C=5 in H2O)
Conditions
Store at 0-8 °C
General Information
Synonyms
(S-(+)-3-Piperidinecarboxylic acid
CAS Number
59045-82-8
Purity
≥ 99% (Titration)
Molecular Formula
C6H11NO2
Molecular Weight
129.16
MDL Number
MFCD01630807
PubChem ID
4498
Melting Point
253-254 °C (dec.)
Appearance
White off-white powder
Optical Rotation
[a]D20 = +5 ± 1.5º (C=5 in H2O)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(+)-nipecotic acid is widely utilized in research focused on

  • Neuroscience: This compound is studied for its potential role as a GABA reuptake inhibitor, which may help in developing treatments for anxiety and epilepsy.
  • Pharmaceutical Development: It serves as a precursor in the synthesis of various pharmaceuticals, particularly those targeting neurological disorders, enhancing drug efficacy.
  • Biochemical Research: Researchers use it to investigate the mechanisms of neurotransmitter regulation, providing insights into brain function and disorders.
  • Analytical Chemistry: It is employed as a standard in chromatographic techniques, aiding in the accurate analysis of complex biological samples.
  • Drug Formulation: Its unique properties allow for the development of novel drug delivery systems, improving the bioavailability of therapeutic agents.

Citations