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Catalog Number:
28435
CAS Number:
33419-42-0
Etoposide
Grade:
USP
Purity:
95 - 105% (Assay on anhydrous basis)
Documents
$33.65 /250MG
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Product Information

Etoposide is a potent chemotherapeutic agent widely utilized in the treatment of various cancers, including testicular cancer, lung cancer, and certain leukemias. This compound functions primarily as a topoisomerase II inhibitor, disrupting DNA replication and leading to cell death, making it a critical component in cancer therapy regimens. Etoposide's unique structure allows it to effectively penetrate cellular membranes, enhancing its bioavailability and therapeutic efficacy.

In addition to its established role in oncology, Etoposide is also being explored for its potential applications in combination therapies, where it may enhance the effectiveness of other anticancer agents. Researchers appreciate its versatility and the ability to tailor treatment protocols based on individual patient needs. With ongoing studies investigating its use in various malignancies and treatment combinations, Etoposide continues to hold promise as a vital tool in the fight against cancer.

CAS Number
33419-42-0
Purity
95 - 105% (Assay on anhydrous basis)
Grade
USP
Molecular Formula
C29H32O13
Molecular Weight
588.56
MDL Number
MFCD00869325
PubChem ID
3310
Appearance
White solid or crystalline powder
Optical Rotation
[a]D20 = -110 to -118 º (C=5 mg/mL in chloroform and methanol 9:1)
Conditions
Store at 0 - 8 °C
General Information
CAS Number
33419-42-0
Purity
95 - 105% (Assay on anhydrous basis)
Grade
USP
Molecular Formula
C29H32O13
Molecular Weight
588.56
MDL Number
MFCD00869325
PubChem ID
3310
Appearance
White solid or crystalline powder
Optical Rotation
[a]D20 = -110 to -118 º (C=5 mg/mL in chloroform and methanol 9:1)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Etoposide is widely utilized in research focused on:

  • Cancer Treatment: Etoposide is primarily used as a chemotherapeutic agent for treating various cancers, including testicular cancer and small cell lung cancer. Its effectiveness in disrupting DNA synthesis makes it a critical component in combination therapies.
  • Pharmaceutical Development: In the pharmaceutical industry, etoposide serves as a key compound in the development of new cancer therapies. Researchers are exploring its potential in combination with other drugs to enhance efficacy and reduce side effects.
  • Cell Biology Research: Etoposide is employed in laboratory settings to induce DNA damage in cell cultures, allowing scientists to study cellular responses to DNA damage and repair mechanisms, which is essential for understanding cancer biology.
  • Veterinary Medicine: This compound is also being investigated for its applications in veterinary oncology, providing treatment options for pets diagnosed with certain types of cancer, thus improving their quality of life.
  • Drug Resistance Studies: Etoposide is used in research to study mechanisms of drug resistance in cancer cells, helping to identify new strategies to overcome resistance and improve treatment outcomes for patients.

Citations