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Catalog Number:
26457
CAS Number:
942518-20-9
L-2-(Fmoc-amino)-4-azidobutanoic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-Dab(N3)-OH, (2S)-N-Fmoc-4-azido-butanoic acid
Documents
$95.60 /100MG
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Product Information

Fmoc-Dab(N3)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique azido group enhances its utility in click chemistry, allowing for efficient conjugation reactions that are pivotal in bioconjugation and the development of novel therapeutics. Researchers appreciate Fmoc-Dab(N3)-OH for its ability to facilitate the creation of complex peptide structures, making it an invaluable tool in the fields of medicinal chemistry and biochemistry.

In addition to its role in peptide synthesis, Fmoc-Dab(N3)-OH can be employed in the development of targeted drug delivery systems and in the design of biomaterials. Its stability and reactivity make it an ideal candidate for applications in drug discovery and the creation of peptide-based vaccines. By integrating this compound into their research, scientists can explore innovative approaches to therapeutic development, enhancing the efficacy and specificity of their drug candidates.

Synonyms
Fmoc-Dab(N3)-OH, (2S)-N-Fmoc-4-azido-butanoic acid
CAS Number
942518-20-9
Purity
≥ 99% (HPLC)
Molecular Formula
C19H18N4O4
Molecular Weight
366.38
MDL Number
MFCD11052920
PubChem ID
74396372
Melting Point
122 - 129 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -28 ± 2 º (C=1 in DMF)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-Dab(N3)-OH, (2S)-N-Fmoc-4-azido-butanoic acid
CAS Number
942518-20-9
Purity
≥ 99% (HPLC)
Molecular Formula
C19H18N4O4
Molecular Weight
366.38
MDL Number
MFCD11052920
PubChem ID
74396372
Melting Point
122 - 129 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -28 ± 2 º (C=1 in DMF)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Dab(N3)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of azide functionality which can be further modified for various applications.
  • Drug Development: Its unique structure enables researchers to explore new therapeutic agents by facilitating the development of peptide-based drugs that can target specific biological pathways.
  • Bioconjugation: The azide group allows for click chemistry applications, enabling the efficient conjugation of biomolecules, which is essential in creating targeted drug delivery systems and diagnostic tools.
  • Protein Engineering: This compound can be used in the modification of proteins, enhancing their stability or activity, which is crucial for developing more effective biopharmaceuticals.
  • Research in Chemical Biology: It plays a significant role in studying protein interactions and functions, providing insights that can lead to breakthroughs in understanding complex biological systems.

Citations