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Catalog Number:
24636
CAS Number:
98045-03-5
Boc-Asp-OMe
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-aspartic acid α-methyl ester
Documents
$18.53 /1G
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Product Information

Boc-Asp-OMe is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound, also known as N-tert-butoxycarbonyl-L-aspartic acid methyl ester, serves as a key building block for the development of bioactive peptides and proteins. Its unique Boc (tert-butoxycarbonyl) protecting group allows for selective deprotection, facilitating the synthesis of complex peptide structures. Researchers appreciate Boc-Asp-OMe for its stability and compatibility with various coupling reagents, making it an ideal choice for solid-phase peptide synthesis.

In addition to its applications in peptide synthesis, Boc-Asp-OMe is instrumental in the design of drug candidates targeting neurological disorders and other therapeutic areas. Its ability to mimic natural amino acids while providing enhanced stability and solubility makes it a valuable tool in medicinal chemistry. With its proven track record in both academic and industrial settings, Boc-Asp-OMe continues to be a preferred choice for researchers aiming to innovate and develop new therapeutic agents.

Synonyms
Boc-L-aspartic acid α-methyl ester
CAS Number
98045-03-5
Purity
≥ 98% (HPLC)
Molecular Formula
C10H17NO6
Molecular Weight
247.2
MDL Number
MFCD03094777
PubChem ID
14258702
Melting Point
86 - 93 ºC
Appearance
White powder
Optical Rotation
[a]D20 = -20 ± 2º (C=2 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-aspartic acid α-methyl ester
CAS Number
98045-03-5
Purity
≥ 98% (HPLC)
Molecular Formula
C10H17NO6
Molecular Weight
247.2
MDL Number
MFCD03094777
PubChem ID
14258702
Melting Point
86 - 93 ºC
Appearance
White powder
Optical Rotation
[a]D20 = -20 ± 2º (C=2 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-Asp-OMe is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for aspartic acid during peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: In pharmaceutical research, Boc-Asp-OMe is used to create peptide-based drugs, enhancing their stability and bioavailability, which is crucial for effective therapeutic applications.
  • Bioconjugation: It plays a role in bioconjugation processes, where it helps link peptides to other biomolecules, such as antibodies or enzymes, facilitating the development of targeted therapies.
  • Research in Neuroscience: The compound is valuable in studying neurotransmitter pathways, as aspartic acid is a key player in excitatory neurotransmission, aiding in the understanding of neurological disorders.
  • Analytical Chemistry: Boc-Asp-OMe is used in the development of analytical methods for the quantification of aspartic acid in various biological samples, providing insights into metabolic processes.

Citations