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Catalog Number:
24533
CAS Number:
127-07-1
Hydroxyurea
Grade:
Meets USP specifications
Purity:
97.0-103.0% (Assay, dried basis)
Synonym(s):
Hydroxycarbamide
Documents
$20.00 /25G
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Product Information

Hydroxyurea is a versatile chemical compound known for its significant role in various therapeutic applications, particularly in the treatment of certain cancers and sickle cell disease. As a potent antineoplastic agent, Hydroxyurea works by inhibiting DNA synthesis, making it effective in slowing down the growth of cancer cells. Its ability to increase fetal hemoglobin levels also provides a therapeutic benefit for patients with sickle cell anemia, reducing the frequency of painful crises and other complications associated with the disease.

In addition to its medical applications, Hydroxyurea is utilized in research settings for its ability to induce cell cycle synchronization, allowing scientists to study cellular processes more effectively. Its unique properties, such as solubility in water and stability under various conditions, make it a valuable reagent in laboratory experiments. Hydroxyurea's multifaceted uses in both clinical and research environments highlight its importance in advancing medical treatments and scientific understanding.

Synonyms
Hydroxycarbamide
CAS Number
127-07-1
Purity
97.0-103.0% (Assay, dried basis)
Grade
Meets USP specifications
Molecular Formula
CH4N2O2
Molecular Weight
76.05
MDL Number
MFCD00007943
PubChem ID
3657
Melting Point
? 133 °C (dec.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
Hydroxycarbamide
CAS Number
127-07-1
Purity
97.0-103.0% (Assay, dried basis)
Grade
Meets USP specifications
Molecular Formula
CH4N2O2
Molecular Weight
76.05
MDL Number
MFCD00007943
PubChem ID
3657
Melting Point
? 133 °C (dec.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Hydroxyurea is widely utilized in research focused on:

  • Cancer Treatment: It is commonly used in chemotherapy regimens for certain types of cancer, particularly chronic myeloid leukemia and ovarian cancer, helping to slow down the growth of cancer cells.
  • Sickle Cell Disease Management: Hydroxyurea is effective in increasing fetal hemoglobin levels, which can reduce the frequency of painful sickle cell crises and improve overall patient quality of life.
  • Research on Genetic Disorders: It is used in studies investigating the genetic basis of diseases, as it can induce mutations in model organisms, aiding in the understanding of gene function and disease mechanisms.
  • HIV Treatment: Hydroxyurea has been explored as an adjunct therapy in HIV treatment, as it may enhance the effectiveness of antiretroviral drugs by affecting viral replication.
  • Dermatology Applications: In topical formulations, it is used to treat skin conditions like psoriasis and actinic keratosis due to its ability to promote cell turnover and reduce hyperkeratosis.

Citations