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Catalog Number:
24144
CAS Number:
57476-50-3
tert-Butyl 3-formyl-1H-indole-1-carboxylate
Purity:
≥ 99% (HPLC)
Synonym(s):
3-Formylindole-1-carboxylic acid tert-butyl ester, 1-N-Boc-indole-3-carboxaldehyde
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Product Information

tert-Butyl 3-formyl-1H-indole-1-carboxylate is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This compound features a unique indole structure, which is known for its significant biological activity, making it a valuable building block in the development of pharmaceuticals and agrochemicals. Its tert-butyl ester group enhances solubility and stability, facilitating its application in various chemical reactions, including condensation and acylation processes. Researchers have leveraged this compound in the synthesis of indole derivatives that exhibit promising anti-cancer and anti-inflammatory properties, showcasing its potential in drug discovery.

In addition to its pharmaceutical applications, tert-butyl 3-formyl-1H-indole-1-carboxylate serves as an important intermediate in the production of fine chemicals and agrochemicals. Its ability to undergo diverse transformations allows for the creation of complex molecular architectures, making it a preferred choice for chemists aiming to innovate in synthetic methodologies. With its favorable properties and broad applicability, this compound stands out as a key player in advancing research and development across various fields.

Synonyms
3-Formylindole-1-carboxylic acid tert-butyl ester, 1-N-Boc-indole-3-carboxaldehyde
CAS Number
57476-50-3
Purity
≥ 99% (HPLC)
Molecular Formula
C14H15NO3
Molecular Weight
245.28
MDL Number
MFCD00049230
PubChem ID
2764519
Melting Point
117 - 130 ?C
Appearance
Yellowish to off-white crystalline powder
Conditions
Store at 0-8°C
General Information
Synonyms
3-Formylindole-1-carboxylic acid tert-butyl ester, 1-N-Boc-indole-3-carboxaldehyde
CAS Number
57476-50-3
Purity
≥ 99% (HPLC)
Molecular Formula
C14H15NO3
Molecular Weight
245.28
MDL Number
MFCD00049230
PubChem ID
2764519
Melting Point
117 - 130 ?C
Appearance
Yellowish to off-white crystalline powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

tert-Butyl 3-formyl-1H-indole-1-carboxylate is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: This compound serves as a key intermediate in the synthesis of various pharmaceutical agents, particularly those targeting neurological disorders, enhancing drug development efficiency.
  • Organic Synthesis: It is employed in organic synthesis reactions, particularly for creating complex indole derivatives, which are valuable in medicinal chemistry.
  • Biological Research: Researchers use this compound to study its biological activity, including its potential anti-cancer properties, contributing to the development of new therapeutic agents.
  • Material Science: It finds applications in the development of advanced materials, such as polymers and coatings, due to its unique chemical structure and reactivity.
  • Fluorescent Probes: The compound is utilized in creating fluorescent probes for bioimaging, allowing for better visualization of biological processes in live cells.

Citations