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Catalog Number:
23045
CAS Number:
71865-37-7
Dithio-bis-maleimidoethane
Purity:
≥ 98%
Synonym(s):
DTME
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Product Information

Dithio-bis-maleimidoethane is a versatile compound known for its unique properties and applications in various fields, particularly in bioconjugation and polymer chemistry. This compound features two maleimide groups that enable efficient thiol-reactive chemistry, making it an excellent choice for cross-linking proteins and peptides. Its ability to form stable conjugates is invaluable in the development of targeted drug delivery systems and biopharmaceuticals, where precise attachment of therapeutic agents to biomolecules is crucial. Additionally, Dithio-bis-maleimidoethane is utilized in the synthesis of advanced materials, including hydrogels and nanomaterials, which are essential in biomedical applications such as tissue engineering and regenerative medicine.

Researchers and industry professionals benefit from Dithio-bis-maleimidoethane's high reactivity and specificity, which allow for controlled modifications of biomolecules without compromising their biological activity. Its unique disulfide bond structure provides stability under physiological conditions while enabling easy cleavage under reducing environments, offering flexibility in various applications. This compound stands out for its potential to enhance the efficacy of therapeutic agents and improve the performance of biomaterials, making it a valuable addition to any research or industrial toolkit.

Synonyms
DTME
CAS Number
71865-37-7
Purity
≥ 98%
Molecular Formula
C12H12N2S2O4
Molecular Weight
312.37
MDL Number
MFCD01863385
PubChem ID
191989
Melting Point
124 °C
Appearance
White powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
DTME
CAS Number
71865-37-7
Purity
≥ 98%
Molecular Formula
C12H12N2S2O4
Molecular Weight
312.37
MDL Number
MFCD01863385
PubChem ID
191989
Melting Point
124 °C
Appearance
White powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Dithio-bis-maleimidoethane is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a crosslinker in bioconjugation processes, allowing researchers to attach biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the development of targeted therapies.
  • Drug Delivery Systems: Its unique properties enable the creation of advanced drug delivery systems, where it helps in the controlled release of therapeutic agents, improving treatment efficacy in cancer and other diseases.
  • Polymer Chemistry: In the field of polymer science, it is used to modify polymer properties, leading to materials with improved mechanical strength and thermal stability, which are essential in various industrial applications.
  • Diagnostics: The compound is utilized in diagnostic assays, particularly in the development of sensitive detection methods for biomolecules, aiding in early disease diagnosis and monitoring.
  • Material Science: Its ability to form stable linkages makes it valuable in creating functional materials, such as coatings and adhesives, which are crucial in electronics and automotive industries.

Citations