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Catalog Number:
23002
CAS Number:
484-20-8
5-Methoxypsoralen (Bergapten)
Purity:
98 - 102% (HPLC)
Synonym(s):
4-Methoxyfuro[3,2-g]benzopyrane-7-one, Bergapten
Documents
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Product Information

5-Methoxypsoralen, also known as Bergapten, is a naturally occurring compound with significant applications in the fields of dermatology and phototherapy. This furanocoumarin is primarily extracted from various plants, including the seeds of the grapefruit and the root of the psoralea plant. Its unique ability to enhance the effects of ultraviolet (UV) light makes it a valuable agent in the treatment of skin disorders such as psoriasis and vitiligo. By increasing the skin's sensitivity to UV radiation, 5-Methoxypsoralen facilitates the therapeutic benefits of phototherapy, leading to improved patient outcomes.

In addition to its dermatological applications, 5-Methoxypsoralen is also utilized in research settings for its potential in studying cellular responses to UV light and its role in DNA damage repair mechanisms. Its ability to intercalate into DNA and form cross-links under UV exposure opens avenues for further exploration in cancer research and photobiology. With its dual role in both therapeutic and research applications, 5-Methoxypsoralen stands out as a versatile compound that offers significant benefits to healthcare professionals and researchers alike.

Synonyms
4-Methoxyfuro[3,2-g]benzopyrane-7-one, Bergapten
CAS Number
484-20-8
Purity
98 - 102% (HPLC)
Molecular Formula
C12H8O4
Molecular Weight
216.2
MDL Number
MFCD00010272
PubChem ID
2355
Melting Point
185 - 190 ?C
Appearance
White colored fluffy fine needles
Conditions
Store at 0-8 °C
General Information
Synonyms
4-Methoxyfuro[3,2-g]benzopyrane-7-one, Bergapten
CAS Number
484-20-8
Purity
98 - 102% (HPLC)
Molecular Formula
C12H8O4
Molecular Weight
216.2
MDL Number
MFCD00010272
PubChem ID
2355
Melting Point
185 - 190 ?C
Appearance
White colored fluffy fine needles
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Methoxypsoralen is widely utilized in research focused on

  • Phototherapy for Skin Disorders: This compound is commonly used in treating skin conditions like psoriasis and vitiligo, where it enhances the effectiveness of ultraviolet light therapy, leading to improved skin health.
  • Research in Cancer Treatment: It has been studied for its potential role in cancer therapies, particularly in combination with other drugs to enhance the efficacy of treatment protocols.
  • Natural Product Synthesis: 5-Methoxypsoralen serves as a valuable precursor in the synthesis of various natural products, facilitating the development of new pharmaceuticals and agrochemicals.
  • Antimicrobial Applications: The compound exhibits antimicrobial properties, making it useful in developing treatments for infections, particularly in the field of dermatology.
  • Studying DNA Interaction: It is employed in research to investigate DNA interactions, providing insights into mutagenesis and the mechanisms of action for certain drugs.

Citations