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Catalog Number:
22883
CAS Number:
65-61-2
Acridine Orange hydrochloride hydrate
Purity:
≥ 99% (HPLC)
Synonym(s):
3,6-Bis(dimethylamino)acridine hydrochloride, CI 46005
Documents
$72.31 /1G
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Product Information

Acridine Orange hydrochloride is a vital fluorescent dye widely utilized in biological and medical research. This compound is particularly effective for staining nucleic acids, making it an essential tool in microscopy and flow cytometry. Its unique properties allow for the differentiation between live and dead cells, as it can penetrate living cells and bind to RNA and DNA, providing researchers with valuable insights into cellular health and viability. Additionally, Acridine Orange is employed in various applications, including the detection of apoptotic cells and the study of cellular processes in microbiology and pathology.

The versatility of Acridine Orange hydrochloride extends to its use in clinical diagnostics, where it aids in the identification of certain pathogens and the assessment of cellular responses to treatments. Its ability to emit fluorescence under specific wavelengths enhances its utility in imaging techniques, allowing for precise visualization of cellular structures. Researchers and industry professionals benefit from its cost-effectiveness and ease of use, making it a preferred choice for laboratories focused on cell biology, genetics, and molecular diagnostics.

Synonyms
3,6-Bis(dimethylamino)acridine hydrochloride, CI 46005
CAS Number
65-61-2
Purity
≥ 99% (HPLC)
Molecular Formula
C17H19N3·HCl·xH2O
Molecular Weight
301.82
MDL Number
MFCD00150070
PubChem ID
517204
Melting Point
284 - 287 °C
Appearance
Brunt orange or brick red powder or lumps
Conditions
Store at RT
General Information
Synonyms
3,6-Bis(dimethylamino)acridine hydrochloride, CI 46005
CAS Number
65-61-2
Purity
≥ 99% (HPLC)
Molecular Formula
C17H19N3·HCl·xH2O
Molecular Weight
301.82
MDL Number
MFCD00150070
PubChem ID
517204
Melting Point
284 - 287 °C
Appearance
Brunt orange or brick red powder or lumps
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Acridine Orange hydrochloride is widely utilized in research focused on:

  • Cell Viability Assays: This compound is commonly used in laboratories to assess cell health and viability. It differentiates between live and dead cells, making it essential for researchers studying cell proliferation and cytotoxicity.
  • Fluorescent Microscopy: Acridine Orange is a popular fluorescent dye for staining nucleic acids. It allows researchers to visualize cellular components under a fluorescence microscope, aiding in studies of cellular structures and functions.
  • Microbial Detection: In microbiology, this chemical is used to stain bacteria and fungi, facilitating their identification and enumeration in various samples. Its ability to penetrate cell membranes makes it effective for detecting viable microorganisms.
  • Apoptosis Studies: Acridine Orange is instrumental in apoptosis research as it can indicate changes in cell membrane integrity and mitochondrial function, providing insights into programmed cell death mechanisms.
  • Histological Applications: This compound is also utilized in histology for staining tissue samples, enhancing the visualization of cellular morphology and pathology in various medical research fields.

Citations