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Catalog Number:
22720
CAS Number:
1217739-96-2
R-(1-Fmoc-piperidin-3-yl)acetic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
(R-Fmoc-(3-carboxymethyl)piperidine
Documents
$113.87 /25MG
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Product Information

(R)-(1-Fmoc-piperidin-3-yl)acetic acid is a versatile compound widely utilized in the field of medicinal chemistry and peptide synthesis. This compound serves as a crucial building block for the development of peptide-based therapeutics, offering researchers a reliable method for introducing piperidine moieties into their molecular designs. Its unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy deprotection under mild conditions, making it an ideal choice for sequential synthesis in solid-phase peptide synthesis (SPPS).

The compound's structural features enhance its solubility and stability, which are essential for various biological applications, including drug formulation and delivery systems. Additionally, (R)-(1-Fmoc-piperidin-3-yl)acetic acid can be employed in the synthesis of bioactive compounds, providing a pathway for the creation of novel pharmaceuticals with improved efficacy and reduced side effects. Its compatibility with a range of coupling reagents further expands its utility in synthetic organic chemistry, making it a valuable asset for both academic and industrial researchers.

Synonyms
(R-Fmoc-(3-carboxymethyl)piperidine
CAS Number
1217739-96-2
Purity
≥ 98% (HPLC)
Molecular Formula
C22H23NO4
Molecular Weight
365.43
MDL Number
MFCD09264214
PubChem ID
4251851
Appearance
White powder
Optical Rotation
[a]D = +22 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
(R-Fmoc-(3-carboxymethyl)piperidine
CAS Number
1217739-96-2
Purity
≥ 98% (HPLC)
Molecular Formula
C22H23NO4
Molecular Weight
365.43
MDL Number
MFCD09264214
PubChem ID
4251851
Appearance
White powder
Optical Rotation
[a]D = +22 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(1-Fmoc-piperidin-3-yl)acetic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures.
  • Drug Development: It plays a crucial role in medicinal chemistry for developing new pharmaceuticals, especially in designing compounds that target specific biological pathways.
  • Bioconjugation: The chemical is used in bioconjugation techniques, facilitating the attachment of biomolecules to drugs or imaging agents, enhancing their efficacy and targeting capabilities.
  • Research in Neuroscience: Its derivatives are explored in neuroscience research to understand receptor interactions and develop potential treatments for neurological disorders.
  • Analytical Chemistry: The compound is employed in analytical methods to study the interactions of various biomolecules, aiding in the development of new analytical techniques.

Citations