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Catalog Number:
22649
CAS Number:
1014019-74-9, 959580-70-2
(2S,4R)-Fmoc-4-(2-naphthylmethyl)pyrrolidine-2-carboxylic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
(2S,4R)-Fmoc-4-(2-naphthylmethyl)-Pro-OH
Documents
$174.96 /25MG
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Product Information

The compound (2S,4R)-Fmoc-4-(2-naphthylmethyl)pyrrolidine-2-carboxylic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which provides stability and ease of handling during synthesis. Its unique naphthylmethyl side chain enhances the compound's hydrophobic properties, making it particularly valuable in the development of peptide-based pharmaceuticals and research applications. Researchers appreciate its ability to facilitate the formation of complex peptide structures, enabling the exploration of novel therapeutic agents.

In addition to its role in peptide synthesis, this compound is also significant in the study of structure-activity relationships (SAR) in drug development. Its distinctive structural features allow for the design of potent inhibitors and modulators in various biological pathways. With its high purity and reliable performance, (2S,4R)-Fmoc-4-(2-naphthylmethyl)pyrrolidine-2-carboxylic acid stands out as a preferred choice for professionals seeking to advance their research and development efforts in the pharmaceutical industry.

Synonyms
(2S,4R)-Fmoc-4-(2-naphthylmethyl)-Pro-OH
CAS Number
1014019-74-9, 959580-70-2
Purity
≥ 98% (HPLC)
Molecular Formula
C31H27NO4
Molecular Weight
477.56
MDL Number
MFCD04115786
PubChem ID
73358301
Melting Point
153 - 165 ?C
Appearance
White powder
Optical Rotation
[a]D25 = -18.4 ± 2 º (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(2S,4R)-Fmoc-4-(2-naphthylmethyl)-Pro-OH
CAS Number
1014019-74-9, 959580-70-2
Purity
≥ 98% (HPLC)
Molecular Formula
C31H27NO4
Molecular Weight
477.56
MDL Number
MFCD04115786
PubChem ID
73358301
Melting Point
153 - 165 ?C
Appearance
White powder
Optical Rotation
[a]D25 = -18.4 ± 2 º (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2S,4R)-Fmoc-4-(2-naphthylmethyl)pyrrolidine-2-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups, thus enhancing the efficiency of the process.
  • Drug Development: Its unique structure aids in the design of novel pharmaceuticals, particularly in creating compounds with improved bioavailability and efficacy, which is crucial in the pharmaceutical industry.
  • Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of biomolecules to drugs, which can improve targeting and reduce side effects in therapeutic applications.
  • Material Science: It finds applications in developing advanced materials, such as polymers and nanomaterials, which can be utilized in various fields, including electronics and biotechnology.
  • Research in Organic Chemistry: This chemical is a valuable tool for organic chemists in exploring reaction mechanisms and developing new synthetic methodologies, contributing to advancements in the field.

Citations