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Catalog Number:
22163
CAS Number:
73573-88-3
Mevastatin
Purity:
≥ 98% (HPLC)
Synonym(s):
Compactin, ML-236B
Antibiotic
Documents
$58.39 /250MG
Pack Size Availability Price
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Product Information

Mevastatin is a potent statin compound recognized for its role in cholesterol management and cardiovascular health. As a competitive inhibitor of HMG-CoA reductase, it effectively reduces low-density lipoprotein (LDL) cholesterol levels, making it a valuable asset in the treatment of hyperlipidemia. This compound has been extensively studied for its ability to lower cholesterol, thereby potentially reducing the risk of heart disease and stroke. Researchers and healthcare professionals appreciate Mevastatin for its efficacy in lipid regulation, and it serves as a foundational compound in the development of various cholesterol-lowering therapies.

In addition to its primary use in managing cholesterol levels, Mevastatin has shown promise in various research applications, including studies on metabolic syndrome and inflammation. Its unique structure allows for modifications that can enhance its therapeutic profile, making it a subject of interest in pharmaceutical development. Mevastatin's established safety profile and effectiveness in clinical settings further underscore its relevance in both research and therapeutic applications, providing a reliable option for professionals seeking to address lipid-related health issues.

Synonyms
Compactin, ML-236B
CAS Number
73573-88-3
Purity
≥ 98% (HPLC)
Molecular Formula
C23H34O5
Molecular Weight
390.51
MDL Number
MFCD05662341
PubChem ID
2854
Melting Point
151-155 °C
Appearance
White to yellowish crystalline powder
Optical Rotation
[a]D20 = +280 to +295° (C=0.48 in Acetone)
Conditions
Store at 0-8 °C
General Information
Synonyms
Compactin, ML-236B
CAS Number
73573-88-3
Purity
≥ 98% (HPLC)
Molecular Formula
C23H34O5
Molecular Weight
390.51
MDL Number
MFCD05662341
PubChem ID
2854
Melting Point
151-155 °C
Appearance
White to yellowish crystalline powder
Optical Rotation
[a]D20 = +280 to +295° (C=0.48 in Acetone)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Mevastatin is widely utilized in research focused on:

  • Cholesterol Management: As a statin, it effectively lowers cholesterol levels, making it valuable in the treatment of hyperlipidemia and cardiovascular diseases.
  • Pharmaceutical Development: It serves as a model compound for developing new cholesterol-lowering medications, aiding researchers in understanding statin mechanisms and improving drug efficacy.
  • Biochemical Research: Mevastatin is used to study the effects of cholesterol synthesis inhibition on cellular processes, providing insights into metabolic pathways and disease mechanisms.
  • Clinical Trials: It plays a crucial role in clinical studies assessing the long-term effects of statin therapy on heart health, helping to establish guidelines for patient care.
  • Comparative Studies: Researchers utilize it to compare the effectiveness and safety of newer statins, contributing to informed decisions in prescribing practices.

Citations