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Catalog Number:
22126
CAS Number:
4342-03-4
Dacarbazine
Purity:
≥ 98% (T)(HPLC)
Synonym(s):
5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide, DTIC
Documents
$129.19 /1G
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Product Information

Dacarbazine is a potent antineoplastic agent widely utilized in the treatment of various cancers, including melanoma, Hodgkin's lymphoma, and soft tissue sarcomas. This compound functions as an alkylating agent, disrupting DNA synthesis and ultimately inhibiting tumor growth. Its unique structure, characterized by the presence of a diazene group, enhances its reactivity, making it effective in targeting rapidly dividing cancer cells. Dacarbazine is often administered in combination with other chemotherapeutic agents, maximizing therapeutic efficacy and improving patient outcomes.

In addition to its established use in oncology, Dacarbazine is also being explored in clinical trials for other malignancies, showcasing its versatility in cancer treatment protocols. Researchers appreciate its relatively favorable safety profile compared to other chemotherapeutics, allowing for better patient tolerance. With ongoing studies investigating its potential in combination therapies, Dacarbazine remains a critical component in the evolving landscape of cancer treatment, offering hope for improved survival rates and quality of life for patients.

Synonyms
5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide, DTIC
CAS Number
4342-03-4
Purity
≥ 98% (T)(HPLC)
Molecular Formula
C6H10N6O
Molecular Weight
182.19
MDL Number
MFCD00057167
PubChem ID
2942
Melting Point
255 ?C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at 0 - 8 °C
General Information
Synonyms
5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide, DTIC
CAS Number
4342-03-4
Purity
≥ 98% (T)(HPLC)
Molecular Formula
C6H10N6O
Molecular Weight
182.19
MDL Number
MFCD00057167
PubChem ID
2942
Melting Point
255 ?C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Dacarbazine is widely utilized in research focused on

  • Cancer Treatment: Primarily used as a chemotherapy agent for treating melanoma and Hodgkin's lymphoma, offering a vital option for patients with these conditions.
  • Clinical Trials: Frequently involved in clinical studies to assess its efficacy in combination therapies, helping to advance cancer treatment protocols.
  • Pharmaceutical Development: Serves as a reference compound in drug formulation research, aiding in the development of new anticancer drugs.
  • Biochemical Research: Utilized in laboratory settings to study cellular responses to chemotherapy, providing insights into cancer cell behavior and resistance mechanisms.
  • Veterinary Medicine: Occasionally explored for use in treating certain cancers in animals, expanding its application beyond human medicine.

Citations