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Catalog Number:
22070
CAS Number:
32981-86-5
10-Deacetylbaccatin III
Purity:
98 - 102% (Assay)
Documents
$20.00 /25MG
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Product Information

10-Deacetylbaccatin III is a naturally occurring compound derived from the yew tree, known for its significant role in the synthesis of the anticancer drug paclitaxel (Taxol). This compound is recognized for its unique structural features, including multiple hydroxyl groups and a complex tetracyclic framework, which contribute to its biological activity. Researchers and pharmaceutical professionals utilize 10-Deacetylbaccatin III as a key intermediate in the production of taxanes, which are widely used in cancer therapy due to their ability to inhibit cell division. Its effectiveness in targeting various cancers, including ovarian and breast cancer, makes it a valuable asset in medicinal chemistry and drug development.

In addition to its pharmaceutical applications, 10-Deacetylbaccatin III is also being explored for its potential in developing novel therapeutic agents. Its unique properties allow for modifications that can enhance efficacy and reduce side effects compared to traditional treatments. As a result, this compound holds promise for advancing cancer treatment strategies and improving patient outcomes, making it an essential ingredient for researchers and industry professionals focused on innovative cancer therapies.

CAS Number
32981-86-5
Purity
98 - 102% (Assay)
Molecular Formula
C29H36O10
Molecular Weight
544.6
MDL Number
MFCD00132913
PubChem ID
125001
Melting Point
234 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -45 to -40 °
Conditions
Store at 0 - 8 °C
General Information
CAS Number
32981-86-5
Purity
98 - 102% (Assay)
Molecular Formula
C29H36O10
Molecular Weight
544.6
MDL Number
MFCD00132913
PubChem ID
125001
Melting Point
234 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -45 to -40 °
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

10-Deacetylbaccatin III is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a precursor in the synthesis of paclitaxel, a widely used chemotherapy drug, enhancing cancer treatment options.
  • Natural Product Research: It is studied for its potential anti-cancer properties, offering insights into new therapeutic agents derived from natural sources.
  • Biotechnology: Researchers explore its role in plant biotechnology, particularly in the genetic engineering of plants for improved medicinal properties.
  • Cosmetic Formulations: Its antioxidant properties make it a valuable ingredient in skincare products, promoting skin health and protection against environmental stressors.
  • Research on Drug Resistance: It is used in studies to understand and combat drug resistance in cancer cells, providing critical information for developing more effective treatments.

Citations