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Catalog Number:
21759
CAS Number:
475-31-0
Glycocholic acid hydrate
Purity:
≥ 99% (HPLC)
Synonym(s):
Cholylglycine hydrate
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Product Information

Glycocholic acid hydrate is a bile acid derivative that plays a crucial role in various biochemical processes, particularly in digestion and absorption of fats. This compound is recognized for its ability to form micelles, which facilitate the emulsification of dietary lipids, making it invaluable in both pharmaceutical and nutritional applications. Its unique structure allows it to interact effectively with lipid membranes, enhancing the bioavailability of lipid-soluble vitamins and drugs. Researchers often utilize glycocholic acid hydrate in studies related to lipid metabolism, drug formulation, and as a potential therapeutic agent in treating conditions related to bile acid malabsorption.

In the pharmaceutical industry, glycocholic acid hydrate is employed in the development of drug delivery systems, particularly for enhancing the solubility and absorption of poorly soluble compounds. Its biocompatibility and ability to improve the pharmacokinetics of various drugs make it a preferred choice for formulators. Additionally, its application in research extends to studying the mechanisms of action of bile acids and their derivatives, providing insights into metabolic diseases and potential therapeutic interventions. With its multifaceted applications, glycocholic acid hydrate stands out as a valuable compound for both researchers and industry professionals.

Synonyms
Cholylglycine hydrate
CAS Number
475-31-0
Purity
≥ 99% (HPLC)
Molecular Formula
C26H43NO6
Molecular Weight
465.63
MDL Number
MFCD06408004
PubChem ID
755
Appearance
White crystalline powder
Optical Rotation
[a]D20 = +28.0 to +32.5º (C=7.5 in 95% EtOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Cholylglycine hydrate
CAS Number
475-31-0
Purity
≥ 99% (HPLC)
Molecular Formula
C26H43NO6
Molecular Weight
465.63
MDL Number
MFCD06408004
PubChem ID
755
Appearance
White crystalline powder
Optical Rotation
[a]D20 = +28.0 to +32.5º (C=7.5 in 95% EtOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Glycocholic acid hydrate is widely utilized in research focused on:

  • Pharmaceutical Development: It serves as a key ingredient in drug formulations, particularly for enhancing the solubility and bioavailability of poorly soluble drugs, making it valuable in the pharmaceutical industry.
  • Biochemical Research: This compound is used in studies related to bile acids and their role in digestion and metabolism, aiding researchers in understanding liver function and related disorders.
  • Cosmetic Applications: Glycocholic acid hydrate is incorporated into skincare products for its emulsifying properties, helping to improve the texture and absorption of active ingredients in creams and lotions.
  • Food Industry: It is utilized as a food additive to enhance flavor and texture, particularly in dairy products, where it can improve the emulsification of fats.
  • Analytical Chemistry: The compound is employed as a standard in chromatography techniques, assisting in the accurate analysis of bile acids and related compounds in biological samples.

Citations