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Catalog Number:
21690
CAS Number:
16096-97-2
L-Dithiothreitol
Purity:
≥ 95% (Assay by titration)
Synonym(s):
(-)-1,4-Dithio-L-threitol, (-)-Cleland's reagent, (2R,3R-(-)-2,3-Dihydroxy-1,4-butanedithiol
Documents
$110.00 /250MG
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Product Information
Synonyms
(-)-1,4-Dithio-L-threitol, (-)-Cleland's reagent, (2R,3R-(-)-2,3-Dihydroxy-1,4-butanedithiol
CAS Number
16096-97-2
Purity
≥ 95% (Assay by titration)
Molecular Formula
C4H10O2S2
Molecular Weight
154.25
MDL Number
MFCD00064305
PubChem ID
19001
Melting Point
48 - 53 °C
Appearance
White to almost white crystal powder
Optical Rotation
[a]D20 = 22 - 28 ° (C=2.5 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(-)-1,4-Dithio-L-threitol, (-)-Cleland's reagent, (2R,3R-(-)-2,3-Dihydroxy-1,4-butanedithiol
CAS Number
16096-97-2
Purity
≥ 95% (Assay by titration)
Molecular Formula
C4H10O2S2
Molecular Weight
154.25
MDL Number
MFCD00064305
PubChem ID
19001
Melting Point
48 - 53 °C
Appearance
White to almost white crystal powder
Optical Rotation
[a]D20 = 22 - 28 ° (C=2.5 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

L-Dithiothreitol is widely utilized in research focused on:

  • Protein Stabilization: It is commonly used to maintain the reduced state of proteins during purification processes, preventing oxidation and preserving their functional integrity.
  • Cell Culture: In cell biology, it helps to reduce disulfide bonds in proteins, promoting cell viability and enhancing the growth of sensitive cell lines.
  • Biochemical Assays: Researchers use it in various assays to ensure accurate measurements of enzyme activity by keeping proteins in their active forms.
  • Antioxidant Applications: Its reducing properties make it effective in protecting cells from oxidative stress, which is crucial in studies related to aging and disease.
  • Drug Formulation: In pharmaceutical development, it serves as a stabilizing agent for certain drugs, improving their shelf life and efficacy.

Citations