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Catalog Number:
21257
CAS Number:
2747-05-9
4-Methylumbelliferyl acetate
Purity:
≥ 99%
Synonym(s):
7-(Acetyloxy)-4-methyl-2-benzopyrone, 7-Acetoxy-4-methylcoumarin, Acetic acid 4-methylumbelliferyl ester
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$18.53 /1G
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Product Information

4-Methylumbelliferyl acetate is a versatile chemical compound widely utilized in biochemical research and analytical applications. This compound serves as a fluorogenic substrate, particularly in enzyme assays, where it is hydrolyzed by specific enzymes to release 4-methylumbelliferone, a fluorescent product. This property makes it invaluable in studying enzyme kinetics and activity, especially in the fields of molecular biology and biochemistry. Researchers often employ 4-Methylumbelliferyl acetate in assays for enzymes such as alkaline phosphatase and β-glucuronidase, enabling sensitive detection and quantification of enzymatic activity.

In addition to its role in enzyme assays, 4-Methylumbelliferyl acetate is also used in various applications such as histochemistry and cell biology, where it aids in visualizing enzyme activity within tissues and cells. Its high sensitivity and specificity make it a preferred choice for researchers looking to obtain accurate and reliable results. The compound's unique properties, including its ability to produce a strong fluorescent signal upon enzymatic cleavage, provide significant advantages over other substrates, making it an essential tool in both academic and industrial laboratories.

Synonyms
7-(Acetyloxy)-4-methyl-2-benzopyrone, 7-Acetoxy-4-methylcoumarin, Acetic acid 4-methylumbelliferyl ester
CAS Number
2747-05-9
Purity
≥ 99%
Molecular Formula
C12H10O4
Molecular Weight
218.21
MDL Number
MFCD00006865
PubChem ID
366
Melting Point
147-153 ?C
Appearance
White powder
Conditions
Store at 0-8 °C
General Information
Synonyms
7-(Acetyloxy)-4-methyl-2-benzopyrone, 7-Acetoxy-4-methylcoumarin, Acetic acid 4-methylumbelliferyl ester
CAS Number
2747-05-9
Purity
≥ 99%
Molecular Formula
C12H10O4
Molecular Weight
218.21
MDL Number
MFCD00006865
PubChem ID
366
Melting Point
147-153 ?C
Appearance
White powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Methylumbelliferyl acetate is widely utilized in research focused on:

  • Enzyme Activity Assays: This compound serves as a substrate for various enzymes, particularly in studying hydrolases. Its fluorescence upon cleavage makes it ideal for real-time monitoring of enzyme activity.
  • Biochemical Research: It is commonly used in laboratories to investigate metabolic pathways and enzyme kinetics, providing insights into biological processes and potential therapeutic targets.
  • Fluorescent Probes: The compound's fluorescent properties allow it to be used as a probe in cellular imaging, helping researchers visualize enzyme localization and activity within living cells.
  • Drug Development: In pharmaceutical research, it aids in screening potential drug candidates by assessing their effects on specific enzymatic reactions, streamlining the drug discovery process.
  • Environmental Monitoring: This chemical can be employed in assessing the activity of microbial communities in environmental samples, contributing to studies on soil health and pollution degradation.

Citations