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Catalog Number:
20985
CAS Number:
89772-41-8
4-Nitrophenyl-β-D-glucuronic acid sodium salt
Purity:
≥ 99% (ELSD)
Synonym(s):
p-Nitrophenyl-β-D-glucuronide, sodium salt, pNP-β-D-GlcA·Na
Documents
$141.41 /25MG
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Product Information

4-Nitrophenyl-b-D-glucuronic acid sodium salt is a versatile compound widely utilized in biochemical research and pharmaceutical applications. This sodium salt form enhances its solubility and bioavailability, making it an ideal choice for various enzymatic assays and drug metabolism studies. Its unique structure, featuring a nitrophenyl group, allows for specific interactions with biological molecules, facilitating the investigation of glucuronidation processes, which are crucial in drug detoxification and metabolism. Researchers often leverage this compound to explore the pharmacokinetics of drugs, as it serves as a substrate for UDP-glucuronosyltransferases, key enzymes in the liver responsible for drug conjugation.

In addition to its research applications, 4-Nitrophenyl-b-D-glucuronic acid sodium salt can be employed in the development of novel therapeutic agents, particularly in the field of cancer treatment, where understanding drug metabolism is essential for optimizing efficacy and minimizing toxicity. Its ability to mimic natural substrates makes it a valuable tool for studying enzyme kinetics and developing new drug formulations. This compound stands out for its reliability and effectiveness, making it a preferred choice among professionals in the pharmaceutical and biochemical industries.

Synonyms
p-Nitrophenyl-β-D-glucuronide, sodium salt, pNP-β-D-GlcA·Na
CAS Number
89772-41-8
Purity
≥ 99% (ELSD)
Molecular Formula
C12H12NO9·Na
Molecular Weight
337.22
MDL Number
MFCD00798406
PubChem ID
72806563
Appearance
White to off-white powder
Conditions
Store at 0-8°C
General Information
Synonyms
p-Nitrophenyl-β-D-glucuronide, sodium salt, pNP-β-D-GlcA·Na
CAS Number
89772-41-8
Purity
≥ 99% (ELSD)
Molecular Formula
C12H12NO9·Na
Molecular Weight
337.22
MDL Number
MFCD00798406
PubChem ID
72806563
Appearance
White to off-white powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Nitrophenyl-b-D-glucuronic acid sodium salt is widely utilized in research focused on:

  • Drug Development: This compound serves as a valuable substrate in enzyme assays, particularly for studying glucuronidation processes in drug metabolism, helping researchers understand how drugs are processed in the body.
  • Biochemical Research: It is used in the study of glycosyltransferases, enzymes that play a crucial role in carbohydrate metabolism, providing insights into various metabolic pathways.
  • Diagnostic Applications: The compound can be employed in the development of diagnostic tests for liver function, as glucuronidation is a key process in detoxifying substances in the liver.
  • Food Industry: It is utilized in food safety testing to detect the presence of certain contaminants, aiding in ensuring food quality and safety for consumers.
  • Environmental Monitoring: This chemical can be applied in assessing the biodegradability of pollutants, helping researchers evaluate the environmental impact of various compounds.

Citations