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Catalog Number:
17596
CAS Number:
475102-15-9
1-Boc-5-cyano-1H-indole-2-boronic acid
Purity:
≥ 95% (HPLC)
Synonym(s):
N-tert-Butoxycarbonyl-5-cyano-1H-indole-2-boronic acid, 5-Cyano-1-tert-butoxycarbonyl-1H-indole-2-boronic acid
Documents
$51.18 /100MG
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Product Information

1-Boc-5-cyano-1H-indole-2-boronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative features a unique combination of a cyano group and a Boc (tert-butyloxycarbonyl) protecting group, making it an essential building block for the development of complex molecules. Its ability to participate in Suzuki-Miyaura cross-coupling reactions allows researchers to create diverse biaryl compounds, which are critical in the pharmaceutical industry for drug discovery and development.

The compound's stability and reactivity make it particularly valuable in the synthesis of indole-based pharmaceuticals, which are known for their therapeutic properties. Additionally, its boronic acid functionality enables it to form reversible covalent bonds with diols, enhancing its application in sensor technology and material science. Researchers and industry professionals can leverage 1-Boc-5-cyano-1H-indole-2-boronic acid to streamline their synthetic pathways and improve yields in the creation of innovative chemical entities.

Synonyms
N-tert-Butoxycarbonyl-5-cyano-1H-indole-2-boronic acid, 5-Cyano-1-tert-butoxycarbonyl-1H-indole-2-boronic acid
CAS Number
475102-15-9
Purity
≥ 95% (HPLC)
Molecular Formula
C14H15BN2O4
Molecular Weight
286.09
MDL Number
MFCD04114578
PubChem ID
4236497
Appearance
Brown or tan powder
Conditions
Store at 0-8°C
General Information
Synonyms
N-tert-Butoxycarbonyl-5-cyano-1H-indole-2-boronic acid, 5-Cyano-1-tert-butoxycarbonyl-1H-indole-2-boronic acid
CAS Number
475102-15-9
Purity
≥ 95% (HPLC)
Molecular Formula
C14H15BN2O4
Molecular Weight
286.09
MDL Number
MFCD04114578
PubChem ID
4236497
Appearance
Brown or tan powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1-Boc-5-cyano-1H-indole-2-boronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and neurological disorders.
  • Organic Synthesis: It is employed in organic synthesis as a versatile building block for creating complex molecules, enabling researchers to develop novel compounds with specific biological activities.
  • Material Science: The compound is used in the formulation of advanced materials, such as polymers and coatings, which require specific chemical properties for enhanced performance.
  • Bioconjugation: In biochemistry, it facilitates the conjugation of biomolecules, allowing for the development of targeted drug delivery systems that improve therapeutic efficacy.
  • Analytical Chemistry: It can be utilized as a reagent in analytical methods, aiding in the detection and quantification of other compounds in various samples.

Citations