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Catalog Number:
17073
CAS Number:
141774-61-0
2-(N-Boc-aminomethyl)piperidine
Synonym(s):
Piperidin-2-ylmethyl-carbamic acid tert-butyl ester, tert-Butyl piperidin-2-ylmethylcarbamate
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Product Information

2-(N-Boc-aminomethyl)piperidine is a versatile compound widely utilized in organic synthesis and pharmaceutical research. This tert-butyl carbamate derivative is particularly valued for its role as a protecting group in the synthesis of amines, allowing chemists to selectively modify functional groups without interference. Its unique structure provides stability and ease of removal under mild conditions, making it a preferred choice for researchers aiming to streamline complex synthetic pathways.

In the pharmaceutical industry, 2-(N-Boc-aminomethyl)piperidine serves as a crucial intermediate in the development of various bioactive compounds, including potential drug candidates. Its application extends to the synthesis of piperidine derivatives, which are integral to numerous therapeutic agents. Researchers appreciate its compatibility with a range of reaction conditions, enhancing its utility in diverse chemical processes. With its ability to facilitate efficient synthesis and contribute to the development of innovative pharmaceuticals, this compound stands out as a valuable asset for both academic and industrial chemists.

Synonyms
Piperidin-2-ylmethyl-carbamic acid tert-butyl ester, tert-Butyl piperidin-2-ylmethylcarbamate
CAS Number
141774-61-0
Molecular Formula
C11H22N2O2
Molecular Weight
214.31
MDL Number
MFCD02181068
PubChem ID
2756031
Melting Point
95 - 98 ?C
Appearance
White powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Piperidin-2-ylmethyl-carbamic acid tert-butyl ester, tert-Butyl piperidin-2-ylmethylcarbamate
CAS Number
141774-61-0
Molecular Formula
C11H22N2O2
Molecular Weight
214.31
MDL Number
MFCD02181068
PubChem ID
2756031
Melting Point
95 - 98 ?C
Appearance
White powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-(N-Boc-aminomethyl)piperidine is widely utilized in research focused on:

  • Synthetic Chemistry: This compound serves as a versatile building block in the synthesis of various pharmaceuticals and agrochemicals, making it invaluable for researchers developing new drugs or crop protection agents.
  • Medicinal Chemistry: Its structure allows for the modification of bioactive molecules, facilitating the design of potent and selective drug candidates, particularly in the development of central nervous system agents.
  • Peptide Synthesis: The compound is used in the preparation of peptide derivatives, enhancing the stability and bioavailability of therapeutic peptides, which is crucial in drug formulation.
  • Material Science: It can be incorporated into polymer matrices to create materials with tailored properties, such as improved mechanical strength or thermal stability, beneficial for various industrial applications.
  • Bioconjugation: This chemical is employed in bioconjugation strategies to attach biomolecules to surfaces or other molecules, aiding in the development of targeted drug delivery systems and diagnostic tools.

Citations