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Catalog Number:
16962
CAS Number:
957780-59-5
Fmoc-Asn(Trt)-Thr[Psi(Me,Me)Pro]-OH
Purity:
≥ 96% (HPLC)
Synonym(s):
Fmoc-Asn(Trt)-Thr(ΨMe,Mepro)-OH, (4S,5R)-3-[Na-(9-Fluorenylmethyloxycarbonyl)-Nb-trityl-L-asparaginyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
Antibiotic
Documents
$77.82 /1G
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Product Information

Fmoc-Asn(Trt)-Thr[Psi(Me,Me)Pro]-OH is a sophisticated amino acid derivative that plays a pivotal role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry for its ability to enhance the stability and bioavailability of peptides. The Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection during synthesis, making it an ideal choice for researchers focused on complex peptide sequences. Its unique Psi(Me,Me)Pro configuration contributes to the conformational flexibility of peptides, which is crucial for optimizing interactions with biological targets.

In practical applications, Fmoc-Asn(Trt)-Thr[Psi(Me,Me)Pro]-OH is utilized in the design of peptide-based therapeutics, particularly in the development of inhibitors and modulators for various biological pathways. Its trityl (Trt) protection further enhances its stability during synthesis and storage, making it a reliable choice for researchers. The compound's ability to facilitate the creation of cyclic and linear peptides expands its utility in drug discovery, particularly in targeting challenging protein-protein interactions. With its robust profile, this compound is an essential tool for professionals aiming to innovate in peptide chemistry and therapeutic development.

Synonyms
Fmoc-Asn(Trt)-Thr(ΨMe,Mepro)-OH, (4S,5R)-3-[Na-(9-Fluorenylmethyloxycarbonyl)-Nb-trityl-L-asparaginyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
CAS Number
957780-59-5
Purity
≥ 96% (HPLC)
Molecular Formula
C45H43N3O7
Molecular Weight
737.8
MDL Number
MFCD08064322
PubChem ID
129011243
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-Asn(Trt)-Thr(ΨMe,Mepro)-OH, (4S,5R)-3-[Na-(9-Fluorenylmethyloxycarbonyl)-Nb-trityl-L-asparaginyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
CAS Number
957780-59-5
Purity
≥ 96% (HPLC)
Molecular Formula
C45H43N3O7
Molecular Weight
737.8
MDL Number
MFCD08064322
PubChem ID
129011243
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Fmoc-Asn(Trt)-Thr[Psi(Me,Me)Pro] is widely utilized in research focused on:

  • Peptide Synthesis: This compound is essential in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield, which is crucial for drug development and biological research.
  • Bioconjugation: It serves as a building block for bioconjugation processes, enabling the attachment of peptides to various biomolecules, enhancing the efficacy of therapeutic agents in targeted drug delivery systems.
  • Protein Engineering: The compound is used in the design of modified proteins, facilitating the study of protein interactions and functions, which is vital in biotechnology and pharmaceutical research.
  • Research in Neuroscience: Its application in synthesizing neuropeptides aids in understanding neurological pathways and developing treatments for neurodegenerative diseases.
  • Development of Diagnostic Tools: The compound contributes to the creation of peptide-based diagnostics, improving the detection of diseases through more accurate biomarker identification.

Citations