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Catalog Number:
16936
CAS Number:
587854-43-1
Fmoc-Lys(Boc-Cys(Trt))-OH
Purity:
≥ 95% (HPLC)
Synonym(s):
Na-Fmoc-Ne-(S-trityl-N-Boc-L-cysteinyl)-L-lysine
Documents
$190.00 /250MG
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Product Information

Fmoc-Lys(Boc-Cys(Trt))-OH is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective deprotection of amino acids during solid-phase peptide synthesis. The presence of a Boc (tert-butyloxycarbonyl) protected cysteine residue, along with a trityl (Trt) protecting group, enhances its stability and compatibility in various synthetic pathways, making it an ideal choice for researchers focused on complex peptide structures.

This compound is particularly valuable in the development of peptide-based therapeutics and diagnostics, where precise control over amino acid sequences is crucial. Its unique structure allows for the incorporation of sulfur-containing amino acids, which can impart distinct biochemical properties to the resulting peptides. Researchers in the fields of drug development and biomolecular engineering will find Fmoc-Lys(Boc-Cys(Trt))-OH to be an essential building block for creating innovative peptide constructs with enhanced functionality and specificity.

Synonyms
Na-Fmoc-Ne-(S-trityl-N-Boc-L-cysteinyl)-L-lysine
CAS Number
587854-43-1
Purity
≥ 95% (HPLC)
Molecular Formula
C48H51N3O7S
Molecular Weight
814.0
MDL Number
MFCD08064308
PubChem ID
10129644
Melting Point
85 - 93 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = - 6 ±2 °(C=1 in DMF)
Conditions
Store at 0 - 8 °
General Information
Synonyms
Na-Fmoc-Ne-(S-trityl-N-Boc-L-cysteinyl)-L-lysine
CAS Number
587854-43-1
Purity
≥ 95% (HPLC)
Molecular Formula
C48H51N3O7S
Molecular Weight
814.0
MDL Number
MFCD08064308
PubChem ID
10129644
Melting Point
85 - 93 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = - 6 ±2 °(C=1 in DMF)
Conditions
Store at 0 - 8 °
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Lys(Boc-Cys(Trt))-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its protective groups allow for selective reactions, enhancing the efficiency of creating complex peptides.
  • Drug Development: In pharmaceutical research, it is used to develop peptide-based drugs. The unique structure aids in designing molecules that can effectively target specific biological pathways, potentially leading to innovative therapies.
  • Bioconjugation: This chemical is valuable in bioconjugation processes, where it helps attach peptides to other biomolecules, such as antibodies or nanoparticles, improving the delivery and efficacy of therapeutic agents.
  • Diagnostics: It plays a role in the development of diagnostic tools, particularly in assays that require specific peptide interactions. This can enhance the sensitivity and specificity of tests in clinical settings.
  • Research in Protein Engineering: The compound is utilized in studies aimed at modifying proteins for enhanced functionality. Its ability to introduce specific amino acids allows researchers to tailor proteins for various applications in biotechnology.

Citations