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Catalog Number:
16838
CAS Number:
1217837-13-2
Fmoc-D-2,4,5-trifluorophenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-(R)-2,4,5-trifluorophenylalanine
Documents
$120.58 /250MG
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Product Information

Fmoc-D-2,4,5-trifluorophenylalanine is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its unique trifluoromethyl group, which enhances the lipophilicity and metabolic stability of peptides, making it an excellent choice for researchers focused on developing novel therapeutics. The Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection during solid-phase peptide synthesis, facilitating the creation of complex peptide structures with high purity and yield.

In addition to its applications in peptide synthesis, Fmoc-D-2,4,5-trifluorophenylalanine is also utilized in the study of protein interactions and the design of peptide-based inhibitors. Its distinctive properties enable researchers to explore new avenues in drug discovery, particularly in targeting challenging biological pathways. This compound stands out among similar amino acid derivatives due to its enhanced stability and versatility, making it an indispensable tool for both academic and industrial applications.

Synonyms
Fmoc-(R)-2,4,5-trifluorophenylalanine
CAS Number
1217837-13-2
Purity
≥ 98% (HPLC)
Molecular Formula
C24H18F3NO4
Molecular Weight
441.4
MDL Number
MFCD06659134
PubChem ID
53398422
Appearance
Light grey to white solid
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-(R)-2,4,5-trifluorophenylalanine
CAS Number
1217837-13-2
Purity
≥ 98% (HPLC)
Molecular Formula
C24H18F3NO4
Molecular Weight
441.4
MDL Number
MFCD06659134
PubChem ID
53398422
Appearance
Light grey to white solid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-2,4,5-trifluorophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active compounds.
  • Drug Development: Its unique trifluorophenyl group enhances the bioactivity of peptides, making it valuable in the design of new drugs targeting specific diseases.
  • Bioconjugation: The Fmoc protecting group allows for selective reactions, facilitating the attachment of peptides to other molecules, which is crucial in creating targeted therapies.
  • Research in Fluorinated Compounds: The incorporation of fluorine atoms can improve the metabolic stability of compounds, making it a focus in medicinal chemistry for enhancing drug efficacy.
  • Protein Engineering: This compound is used in modifying proteins to study their structure and function, aiding in the development of novel biotechnological applications.

Citations