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Catalog Number:
16814
CAS Number:
1217733-50-0
Fmoc-D-2,4-dinitrophenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Phe(2,4-DiNO2)-OH, (R)-Fmoc-2-amino-3-(2,4-dinitrophenyl)propionic acid
Documents
$58.39 /25MG
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Product Information

Fmoc-D-2,4-dinitrophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique dinitrophenyl group that enhances its reactivity, making it an excellent choice for researchers focused on developing novel peptides and biomolecules. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy deprotection under mild conditions, facilitating streamlined synthesis processes.

In the pharmaceutical industry, Fmoc-D-2,4-dinitrophenylalanine is particularly valuable for creating targeted therapeutics and studying protein interactions. Its distinct properties enable researchers to explore structure-activity relationships in drug design, providing insights into molecular mechanisms and enhancing the efficacy of therapeutic agents. Additionally, its application in solid-phase peptide synthesis allows for the efficient assembly of complex peptide sequences, making it an essential tool for chemists and biochemists alike.

Synonyms
Fmoc-D-Phe(2,4-DiNO2)-OH, (R)-Fmoc-2-amino-3-(2,4-dinitrophenyl)propionic acid
CAS Number
1217733-50-0
Purity
≥ 99% (HPLC)
Molecular Formula
C24H19N3O8
Molecular Weight
477.42
MDL Number
MFCD08166746
PubChem ID
53398421
Melting Point
175 - 181 ?C
Appearance
Yellowish powder
Optical Rotation
[a]D25 = 5 ± 1 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Phe(2,4-DiNO2)-OH, (R)-Fmoc-2-amino-3-(2,4-dinitrophenyl)propionic acid
CAS Number
1217733-50-0
Purity
≥ 99% (HPLC)
Molecular Formula
C24H19N3O8
Molecular Weight
477.42
MDL Number
MFCD08166746
PubChem ID
53398421
Melting Point
175 - 181 ?C
Appearance
Yellowish powder
Optical Rotation
[a]D25 = 5 ± 1 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-2,4-dinitrophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing for the efficient assembly of complex peptides with high purity.
  • Bioconjugation: Its unique dinitrophenyl group enables effective conjugation with various biomolecules, facilitating the development of targeted drug delivery systems.
  • Fluorescent Labeling: The Fmoc protecting group can be easily removed under mild conditions, making it suitable for creating fluorescently labeled peptides for imaging applications in biological research.
  • Analytical Chemistry: Used as a standard in chromatographic techniques, it helps in the quantification and analysis of peptide mixtures, ensuring accurate results in research studies.
  • Drug Development: Its structural properties allow for the exploration of new therapeutic agents, particularly in the design of inhibitors targeting specific enzymes or receptors in disease pathways.

Citations