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Catalog Number:
16649
CAS Number:
1217706-09-6
Fmoc-(S)-3-thienylglycine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-(3-thienyl)glycine
Documents
$70.50 /25MG
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Product Information

Fmoc-(S)-3-thienylglycine is a valuable amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of complex peptides. Its unique thienyl side chain enhances the compound's bioactivity and structural diversity, making it a preferred choice for researchers focused on developing novel therapeutic agents.

In practical applications, Fmoc-(S)-3-thienylglycine is particularly relevant in the pharmaceutical industry for the design of peptide-based drugs, especially those targeting specific receptors or enzymes. Its ability to facilitate the synthesis of cyclic peptides and other complex structures allows for greater innovation in drug development. Additionally, its compatibility with various coupling reagents and solid-phase synthesis techniques makes it an indispensable tool for chemists aiming to streamline their workflows and improve yields in peptide synthesis.

Synonyms
Fmoc-L-(3-thienyl)glycine
CAS Number
1217706-09-6
Purity
≥ 97% (HPLC)
Molecular Formula
C21H17NO4S
Molecular Weight
379.43
MDL Number
MFCD02682480
PubChem ID
24729667
Melting Point
186 - 192 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 60 ± 1 º (C=1 in DMF) [a]D25 = 63 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-(3-thienyl)glycine
CAS Number
1217706-09-6
Purity
≥ 97% (HPLC)
Molecular Formula
C21H17NO4S
Molecular Weight
379.43
MDL Number
MFCD02682480
PubChem ID
24729667
Melting Point
186 - 192 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 60 ± 1 º (C=1 in DMF) [a]D25 = 63 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-3-thienylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various conditions makes it a preferred choice in solid-phase peptide synthesis.
  • Drug Development: Researchers leverage its unique structure to design novel therapeutics, particularly in the field of anti-cancer agents, where thienyl derivatives show promising biological activity.
  • Bioconjugation: The compound is used to create bioconjugates, enhancing the delivery of drugs to specific cells or tissues, which is crucial in targeted therapy applications.
  • Material Science: In the development of new materials, Fmoc-(S)-3-thienylglycine can be incorporated into polymers to impart specific properties, such as increased conductivity or enhanced mechanical strength.
  • Analytical Chemistry: It is employed as a standard in various analytical techniques, aiding in the quantification and characterization of complex mixtures in research laboratories.

Citations