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Catalog Number:
16640
CAS Number:
211682-13-2
Fmoc-(S)-2-thienylglycine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-(2-thienyl)glycine
Documents
$150.90 /100MG
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Product Information

Fmoc-(S)-2-thienylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique thienyl side chain that enhances its application in the design of bioactive peptides, making it an essential building block for researchers in medicinal chemistry and pharmaceutical development. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing stability during synthesis.

Researchers have found Fmoc-(S)-2-thienylglycine particularly useful in the development of peptides with specific biological activities, including those targeting receptors or enzymes. Its distinct structure not only contributes to the stability and solubility of synthesized peptides but also aids in the exploration of structure-activity relationships (SAR) in drug design. With its ability to enhance the pharmacological properties of peptides, this compound stands out as a valuable tool for scientists aiming to innovate in therapeutic applications.

Synonyms
Fmoc-D-(2-thienyl)glycine
CAS Number
211682-13-2
Purity
≥ 98% (HPLC)
Molecular Formula
C21H17NO4S
Molecular Weight
379.43
MDL Number
MFCD07371939
PubChem ID
46737303
Melting Point
186 - 192 °C (Lit.)
Appearance
White solid
Optical Rotation
[a]D24 = -46 ± 1 º (C=1 in DMF) [a]D25 = -50 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-(2-thienyl)glycine
CAS Number
211682-13-2
Purity
≥ 98% (HPLC)
Molecular Formula
C21H17NO4S
Molecular Weight
379.43
MDL Number
MFCD07371939
PubChem ID
46737303
Melting Point
186 - 192 °C (Lit.)
Appearance
White solid
Optical Rotation
[a]D24 = -46 ± 1 º (C=1 in DMF) [a]D25 = -50 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-2-thienylglycine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids while preventing unwanted reactions.
  • Drug Development: Its unique structure makes it valuable in designing novel pharmaceutical compounds, particularly in the development of drugs targeting specific biological pathways.
  • Bioconjugation: Fmoc-(S)-2-thienylglycine can be used to create bioconjugates, enhancing the delivery of therapeutic agents by improving their stability and solubility.
  • Research in Neuroscience: This compound is instrumental in studying neuropeptides, aiding researchers in understanding their roles in neurological functions and disorders.
  • Custom Synthesis: It is often employed in custom synthesis projects, providing researchers with tailored solutions for their specific chemical needs, particularly in academia and biotech industries.

Citations