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Catalog Number:
16634
CAS Number:
167938-56-9
S-1-(Boc-amino)-2-propanol
Purity:
≥ 99% (Chiral purity)
Synonym(s):
(S-tert-Butyl (2-hydroxypropyl)carbamate, Boc-(S-1-amino-2-propanol
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Product Information

Boc-(S)-1-amino-2-propanol is a versatile compound widely utilized in the synthesis of pharmaceuticals and agrochemicals. This chiral amino alcohol serves as a crucial building block in the development of various bioactive molecules, particularly in the production of peptide-based drugs. Its unique tert-butoxycarbonyl (Boc) protecting group allows for selective reactions, making it an essential reagent in organic synthesis. Researchers appreciate its ability to enhance the solubility and stability of compounds, facilitating smoother reaction processes and improving yields.

In addition to its applications in medicinal chemistry, Boc-(S)-1-amino-2-propanol is also employed in the formulation of chiral catalysts and ligands, which are vital in asymmetric synthesis. Its favorable properties, such as high purity and excellent reactivity, make it a preferred choice among professionals in the pharmaceutical and chemical industries. With its growing relevance in drug discovery and development, this compound holds significant potential for researchers looking to innovate and improve existing methodologies.

Synonyms
(S-tert-Butyl (2-hydroxypropyl)carbamate, Boc-(S-1-amino-2-propanol
CAS Number
167938-56-9
Purity
≥ 99% (Chiral purity)
Molecular Formula
C8H17NO3
Molecular Weight
175.23
MDL Number
MFCD04974340
PubChem ID
9920508
Appearance
Clear and colorless liquid
Boiling Point
95-100 ?C/1.2 mmHg
Optical Rotation
[a]D20 = +22 to +25º (C=1 in CHCl3
Conditions
Store at 0-8 °C
General Information
Synonyms
(S-tert-Butyl (2-hydroxypropyl)carbamate, Boc-(S-1-amino-2-propanol
CAS Number
167938-56-9
Purity
≥ 99% (Chiral purity)
Molecular Formula
C8H17NO3
Molecular Weight
175.23
MDL Number
MFCD04974340
PubChem ID
9920508
Appearance
Clear and colorless liquid
Boiling Point
95-100 ?C/1.2 mmHg
Optical Rotation
[a]D20 = +22 to +25º (C=1 in CHCl3
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-(S)-1-amino-2-propanol is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of chiral drugs, enhancing their efficacy and safety profiles.
  • Peptide Synthesis: It is commonly used in solid-phase peptide synthesis, providing a protective group that allows for the selective modification of amino acids, crucial for creating complex peptide structures.
  • Bioconjugation: The compound is employed in bioconjugation processes, where it aids in attaching biomolecules to surfaces or other molecules, facilitating drug delivery systems and diagnostic applications.
  • Research in Organic Chemistry: It acts as a versatile building block in organic synthesis, allowing researchers to create a wide range of derivatives and explore new chemical reactions.
  • Material Science: Boc-(S)-1-amino-2-propanol is used in the development of functionalized polymers, contributing to advancements in materials with specific properties for applications in coatings and adhesives.

Citations