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Catalog Number:
16625
CAS Number:
130406-30-3
Fmoc-D-phenylalaninol
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-(R-2-amino-3-phenyl-1-propanol
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$65.40 /1G
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Product Information

Fmoc-D-phenylalaninol is a versatile compound widely utilized in the field of peptide synthesis and drug development. This amino acid derivative, recognized for its protective Fmoc (9-fluorenylmethoxycarbonyl) group, plays a crucial role in solid-phase peptide synthesis (SPPS), allowing for the efficient assembly of complex peptides. Its unique structure not only enhances the stability of the amino acid during synthesis but also facilitates the selective deprotection of the Fmoc group, making it an essential tool for researchers and professionals in medicinal chemistry and biochemistry.

In addition to its applications in peptide synthesis, Fmoc-D-phenylalaninol is also valuable in the development of pharmaceutical compounds, particularly in the design of enzyme inhibitors and biologically active molecules. Its ability to serve as a chiral building block allows for the creation of enantiomerically pure substances, which are critical in the production of effective drugs. Researchers appreciate its compatibility with various coupling reagents and its contribution to the overall efficiency of synthetic pathways, making it a preferred choice in laboratories focused on innovative drug discovery and development.

Synonyms
Fmoc-(R-2-amino-3-phenyl-1-propanol
CAS Number
130406-30-3
Purity
≥ 98% (HPLC)
Molecular Formula
C24H23NO3
Molecular Weight
373.45
MDL Number
MFCD00270212
PubChem ID
14539890
Appearance
White to off-white powder
Optical Rotation
[a]D
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-(R-2-amino-3-phenyl-1-propanol
CAS Number
130406-30-3
Purity
≥ 98% (HPLC)
Molecular Formula
C24H23NO3
Molecular Weight
373.45
MDL Number
MFCD00270212
PubChem ID
14539890
Appearance
White to off-white powder
Optical Rotation
[a]D
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-phenylalaninol is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the design of peptide-based drugs, particularly in enhancing the stability and bioavailability of therapeutic peptides.
  • Bioconjugation: Fmoc-D-phenylalaninol is used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other compounds, which is essential in creating targeted drug delivery systems.
  • Research in Neuroscience: This compound is valuable in the synthesis of neuropeptides, which are important for studying neurological pathways and developing treatments for neurodegenerative diseases.
  • Custom Synthesis: Researchers often utilize this compound for custom synthesis projects, enabling the creation of novel compounds tailored to specific experimental needs.

Citations