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Catalog Number:
16607
CAS Number:
112068-01-6
(S)-(-)-Diphenyl-2-pyrrolidinemethanol
Purity:
≥ 99% (Chiral HPLC, HPLC)
Synonym(s):
(S)-(-)-2-(Diphenylhydroxymethyl)pyrrolidine
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Product Information

(S)-(-)-Diphenyl-2-pyrrolidinemethanol is a versatile chiral compound widely recognized for its applications in asymmetric synthesis and pharmaceutical development. This compound serves as a valuable building block in the synthesis of various biologically active molecules, particularly in the creation of pharmaceuticals that require specific stereochemistry. Its unique structure, featuring a pyrrolidine ring and two phenyl groups, enhances its ability to act as a chiral auxiliary, facilitating enantioselective reactions. Researchers and industry professionals utilize this compound in the development of novel drugs, particularly in the fields of medicinal chemistry and organic synthesis, where precision in molecular configuration is crucial.

Moreover, (S)-(-)-Diphenyl-2-pyrrolidinemethanol is noted for its effectiveness in catalyzing reactions that yield high enantiomeric excess, making it an essential tool for chemists aiming to produce pure enantiomers. Its stability and compatibility with various reaction conditions further enhance its appeal in laboratory settings. With its proven track record in advancing drug discovery and development, this compound stands out as a key ingredient for researchers focused on innovative therapeutic solutions.

Synonyms
(S)-(-)-2-(Diphenylhydroxymethyl)pyrrolidine
CAS Number
112068-01-6
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C17H19NO
Molecular Weight
253.34
MDL Number
MFCD00075506
PubChem ID
204386
Melting Point
77 - 80 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -67 ± 3 ° (C=0.5% in CHCl3, 25 °C)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(S)-(-)-2-(Diphenylhydroxymethyl)pyrrolidine
CAS Number
112068-01-6
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C17H19NO
Molecular Weight
253.34
MDL Number
MFCD00075506
PubChem ID
204386
Melting Point
77 - 80 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -67 ± 3 ° (C=0.5% in CHCl3, 25 °C)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(-)-Diphenyl-2-pyrrolidinemethanol is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as a chiral building block in the synthesis of various pharmaceuticals, enhancing the efficacy and selectivity of drug candidates.
  • Catalysis: It is employed as a ligand in asymmetric catalysis, improving reaction yields and selectivity in the production of fine chemicals and agrochemicals.
  • Material Science: The compound is used in the development of advanced materials, particularly in creating polymers with enhanced mechanical properties and thermal stability.
  • Biochemical Research: It acts as a tool in studying enzyme mechanisms and interactions, providing insights into biological processes and aiding in drug discovery.
  • Chiral Resolution: This chemical is effective in the separation of racemic mixtures into their enantiomers, which is crucial for producing high-purity compounds in various industries.

Citations