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Catalog Number:
16576
CAS Number:
87691-27-8
Boc-cis-4-hydroxy-L-proline
Purity:
≥ 98% (TLC)
Synonym(s):
(2S,4S-cis-1-N-Boc-4-hydroxy-proline, Boc-(2S,4S-(-)-4-hydroxypyrrolidine-2-carboxylic acid
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Product Information

Boc-cis-4-hydroxy-L-proline is a valuable amino acid derivative widely utilized in the synthesis of peptides and pharmaceuticals. This compound features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal choice for researchers in organic synthesis and medicinal chemistry. Its unique cis configuration and hydroxyl group provide specific reactivity that can be harnessed in the development of bioactive compounds, particularly in the design of peptide-based drugs and biomaterials.

In addition to its applications in drug development, Boc-cis-4-hydroxy-L-proline serves as a key building block in the synthesis of various natural products and complex organic molecules. Its ability to facilitate the formation of peptide bonds while maintaining structural integrity makes it a preferred choice for chemists aiming to create novel therapeutic agents. Researchers can leverage its properties to explore new avenues in drug discovery, particularly in targeting diseases where peptide therapeutics show promise.

Synonyms
(2S,4S-cis-1-N-Boc-4-hydroxy-proline, Boc-(2S,4S-(-)-4-hydroxypyrrolidine-2-carboxylic acid
CAS Number
87691-27-8
Purity
≥ 98% (TLC)
Molecular Formula
C10H17NO5
Molecular Weight
231.25
MDL Number
MFCD02094406
PubChem ID
335255
Melting Point
142-147 °C
Appearance
White to off white powder
Conditions
Store at 0-8°C
General Information
Synonyms
(2S,4S-cis-1-N-Boc-4-hydroxy-proline, Boc-(2S,4S-(-)-4-hydroxypyrrolidine-2-carboxylic acid
CAS Number
87691-27-8
Purity
≥ 98% (TLC)
Molecular Formula
C10H17NO5
Molecular Weight
231.25
MDL Number
MFCD02094406
PubChem ID
335255
Melting Point
142-147 °C
Appearance
White to off white powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-cis-4-hydroxy-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of pharmaceuticals targeting various diseases.
  • Drug Development: It plays a crucial role in the design of proline-rich peptides, which are important in creating drugs with enhanced stability and bioactivity.
  • Biotechnology: Used in the production of modified proteins, it helps in improving the efficacy of biopharmaceuticals, making them more effective for therapeutic applications.
  • Research in Structural Biology: The unique properties of this compound aid in studying protein folding and stability, which is essential for understanding various biological processes.
  • Cosmetic Formulations: Its hydrophilic nature makes it suitable for use in skin care products, enhancing moisture retention and skin texture.

Citations