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Catalog Number:
16571
CAS Number:
84348-37-8
Boc-4-oxo-L-proline
Purity:
98 - 102% (Assay by titration)
Synonym(s):
(S)-1-Boc-4-oxo-2-pyrrolidinecarboxylic acid, (S)-4-Oxopyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
Documents
$18.53 /1G
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Product Information

Boc-4-oxo-L-proline is a versatile compound widely utilized in the field of organic synthesis and pharmaceutical research. This amino acid derivative, known for its protective Boc (tert-butyloxycarbonyl) group, serves as a crucial building block in peptide synthesis and the development of bioactive molecules. Its unique structure allows for the introduction of various functional groups, making it an essential intermediate in the synthesis of complex peptides and other biologically relevant compounds. Researchers appreciate its stability and ease of handling, which facilitate the design of novel therapeutics and drug candidates.

In addition to its applications in peptide synthesis, Boc-4-oxo-L-proline has shown potential in the development of enzyme inhibitors and other medicinal chemistry applications. Its ability to mimic natural amino acids while providing additional functional versatility makes it a valuable tool for chemists and biochemists alike. Whether you are engaged in academic research or industrial applications, Boc-4-oxo-L-proline offers the reliability and performance needed to advance your projects effectively.

Synonyms
(S)-1-Boc-4-oxo-2-pyrrolidinecarboxylic acid, (S)-4-Oxopyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
CAS Number
84348-37-8
Purity
98 - 102% (Assay by titration)
Molecular Formula
C10H15NO5
Molecular Weight
229.23
MDL Number
MFCD01860669
PubChem ID
4150645
Melting Point
149 - 163 ?C (dec.)
Appearance
White solid
Optical Rotation
[a]D21 = 20 ± 2 º (C= 0.49 in Acetone)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(S)-1-Boc-4-oxo-2-pyrrolidinecarboxylic acid, (S)-4-Oxopyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
CAS Number
84348-37-8
Purity
98 - 102% (Assay by titration)
Molecular Formula
C10H15NO5
Molecular Weight
229.23
MDL Number
MFCD01860669
PubChem ID
4150645
Melting Point
149 - 163 ?C (dec.)
Appearance
White solid
Optical Rotation
[a]D21 = 20 ± 2 º (C= 0.49 in Acetone)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-4-oxo-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of biologically active compounds. Its protective Boc (tert-butyloxycarbonyl) group allows for selective reactions, enhancing the efficiency of peptide assembly.
  • Drug Development: In pharmaceutical research, Boc-4-oxo-L-proline is explored for its potential in creating novel drug candidates. Its unique structure can lead to compounds with improved efficacy and specificity, addressing unmet medical needs.
  • Biochemical Studies: Researchers utilize this compound to study enzyme interactions and metabolic pathways. Its role in various biochemical processes helps in understanding disease mechanisms and developing targeted therapies.
  • Material Science: The compound is investigated for its application in creating advanced materials, such as polymers and hydrogels, which can be used in drug delivery systems or tissue engineering, providing innovative solutions in medical technology.
  • Analytical Chemistry: Boc-4-oxo-L-proline is employed as a standard in analytical methods, aiding in the quantification of related compounds in complex mixtures, thus enhancing the accuracy of analytical results in various research fields.

Citations