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Catalog Number:
16195
CAS Number:
1247791-23-6
Fmoc-D-methionine sulfone
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Met(O2)-OH
Documents
$55.40 /250MG
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Product Information

Fmoc-D-methionine sulfone is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its sulfone group enhances the compound's stability and solubility, making it particularly advantageous in various organic synthesis applications. Researchers often employ Fmoc-D-methionine sulfone in the development of bioactive peptides, which are crucial in drug discovery and development processes.

The unique properties of Fmoc-D-methionine sulfone allow for efficient coupling reactions, facilitating the formation of complex peptide structures with high purity and yield. Its application extends to the synthesis of peptide-based therapeutics and the study of protein interactions, providing significant benefits in both academic and industrial settings. With its reliable performance and compatibility with standard peptide synthesis protocols, Fmoc-D-methionine sulfone stands out as a preferred choice for professionals in the field.

Synonyms
Fmoc-D-Met(O2)-OH
CAS Number
1247791-23-6
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO6S
Molecular Weight
403.5
MDL Number
MFCD06796896
PubChem ID
22490610
Melting Point
156 - 161 °C
Appearance
White crystalline powder or off-white powder
Optical Rotation
[a]D20 = 12 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Met(O2)-OH
CAS Number
1247791-23-6
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO6S
Molecular Weight
403.5
MDL Number
MFCD06796896
PubChem ID
22490610
Melting Point
156 - 161 °C
Appearance
White crystalline powder or off-white powder
Optical Rotation
[a]D20 = 12 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-methionine sulfone is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the introduction of methionine residues in a controlled manner, which is essential for producing biologically active peptides.
  • Drug Development: It plays a significant role in the pharmaceutical industry, particularly in developing new drugs that require specific amino acid sequences, enhancing the efficacy and specificity of therapeutic agents.
  • Protein Engineering: Researchers use this compound to modify proteins, improving their stability and activity, which is crucial for applications in biotechnology and enzyme design.
  • Bioconjugation: Fmoc-D-methionine sulfone is employed in bioconjugation processes, allowing scientists to attach drugs or labels to proteins, facilitating targeted delivery systems in cancer therapy.
  • Research in Neuroscience: Its application in synthesizing neuropeptides aids in studying neurological functions and disorders, providing insights into potential treatments for conditions like depression and anxiety.

Citations