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Catalog Number:
16194
CAS Number:
76265-70-8
Fmoc-D-methionine sulfoxide
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Met(O)-OH
Documents
$65.40 /250MG
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Product Information

Fmoc-D-methionine sulfoxide is a valuable derivative of methionine, widely utilized in peptide synthesis and pharmaceutical research. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which enhances its stability and solubility, making it an ideal choice for solid-phase peptide synthesis. Its unique sulfoxide functional group not only contributes to its reactivity but also allows for the incorporation of methionine residues in peptides, facilitating the study of protein structure and function. Researchers appreciate its role in producing high-purity peptides, which are essential for drug development and biochemical studies.

In addition to its applications in peptide synthesis, Fmoc-D-methionine sulfoxide is also used in the synthesis of bioactive compounds and as a building block in the development of novel therapeutics. Its ability to improve the yield and efficiency of peptide synthesis processes makes it a preferred choice among chemists and biochemists. With its favorable properties and versatile applications, this compound stands out as a key reagent in the fields of medicinal chemistry and biochemistry.

Synonyms
Fmoc-D-Met(O)-OH
CAS Number
76265-70-8
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO5S
Molecular Weight
387.5
MDL Number
MFCD06796895
PubChem ID
73137231
Melting Point
160-167 ?C
Appearance
White powder
Optical Rotation
[a]D20 = +10 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Met(O)-OH
CAS Number
76265-70-8
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO5S
Molecular Weight
387.5
MDL Number
MFCD06796895
PubChem ID
73137231
Melting Point
160-167 ?C
Appearance
White powder
Optical Rotation
[a]D20 = +10 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-methionine sulfoxide is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the efficient assembly of complex peptide chains.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing new drugs, especially those targeting specific proteins, by modifying peptide sequences to enhance efficacy.
  • Bioconjugation: Researchers use it to create bioconjugates, linking peptides to other biomolecules, which is essential in developing targeted therapies and diagnostics.
  • Protein Engineering: The compound is instrumental in protein engineering applications, where it aids in the design of proteins with improved stability and functionality for various industrial applications.
  • Research in Neuroscience: It is used in studies related to neurotransmitter function and signaling pathways, contributing to advancements in understanding neurological diseases.

Citations