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Catalog Number:
16192
CAS Number:
110990-09-5
Nα-Fmoc-Nε-biotinyl-D-lysine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-D-Lys(biotinyl)-OH
Documents
$65.40 /100MG
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Product Information

Na-Fmoc-Ne-biotinyl-D-lysine is a versatile compound widely utilized in bioconjugation and peptide synthesis, particularly in the fields of molecular biology and biochemistry. This compound features a biotin moiety, which enhances its ability to bind to avidin or streptavidin, making it an invaluable tool for researchers working on protein labeling, purification, and detection. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection during peptide synthesis, facilitating the creation of complex peptide structures with high specificity.

Researchers have effectively employed Na-Fmoc-Ne-biotinyl-D-lysine in various applications, including the development of targeted drug delivery systems and the creation of biosensors. Its unique properties enable the formation of stable conjugates that can be used in assays, imaging, and therapeutic applications. By incorporating this compound into their workflows, professionals can achieve enhanced sensitivity and specificity in their experiments, ultimately leading to more reliable results and advancements in their research.

Synonyms
Fmoc-D-Lys(biotinyl)-OH
CAS Number
110990-09-5
Purity
≥ 97% (HPLC)
Molecular Formula
C31H38N4O6S
Molecular Weight
594.7
MDL Number
MFCD00270742
PubChem ID
5102536
Melting Point
179 - 186 ?C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = 38 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Lys(biotinyl)-OH
CAS Number
110990-09-5
Purity
≥ 97% (HPLC)
Molecular Formula
C31H38N4O6S
Molecular Weight
594.7
MDL Number
MFCD00270742
PubChem ID
5102536
Melting Point
179 - 186 ?C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = 38 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-biotinyl-D-lysine is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for attaching biotin to proteins or peptides, facilitating the study of protein interactions and functions in various biological systems.
  • Drug Development: In pharmaceutical research, it aids in the design of targeted drug delivery systems, enhancing the specificity and efficacy of therapeutic agents.
  • Diagnostics: It plays a crucial role in the development of diagnostic assays, particularly in the detection of biomarkers through biotin-streptavidin interactions, which are highly sensitive and specific.
  • Protein Purification: Researchers use this compound to create affinity tags that simplify the purification process of recombinant proteins, making it easier to obtain high-purity samples for further study.
  • Gene Expression Studies: It is utilized in the development of biotinylated oligonucleotides for studying gene expression, allowing for more accurate tracking and analysis of RNA molecules in cellular contexts.

Citations