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Catalog Number:
16185
CAS Number:
1263047-25-1
Nα-Fmoc-Nγ-(2,4-dinitrophenyl)-D-2,4-diaminobutyric acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Dab(Dnp)-OH
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Product Information

Na-Fmoc-Ng-(2,4-dinitrophenyl)-D-2,4-diaminobutyric acid is a versatile compound widely utilized in peptide synthesis and drug development. This compound features the Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. The presence of the 2,4-dinitrophenyl moiety enhances its utility in various biochemical applications, particularly in the development of targeted therapeutics and diagnostic agents. Researchers appreciate its stability and ease of use, making it an excellent choice for complex peptide sequences.

In addition to its role in peptide synthesis, this compound can be employed in the study of enzyme interactions and as a building block in the design of novel pharmaceuticals. Its unique structure allows for specific modifications that can lead to improved bioactivity and selectivity in drug candidates. With its combination of protective and reactive functionalities, Na-Fmoc-Ng-(2,4-dinitrophenyl)-D-2,4-diaminobutyric acid stands out as a valuable tool for researchers aiming to innovate in the fields of medicinal chemistry and biochemistry.

Synonyms
Fmoc-D-Dab(Dnp)-OH
CAS Number
1263047-25-1
Purity
≥ 99% (HPLC)
Molecular Formula
C25H22N4O8
Molecular Weight
506.5
MDL Number
MFCD06796890
PubChem ID
75627321
Melting Point
115-120 °C
Appearance
Yellow crystalline powder
Optical Rotation
[a]D20 = +10 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Dab(Dnp)-OH
CAS Number
1263047-25-1
Purity
≥ 99% (HPLC)
Molecular Formula
C25H22N4O8
Molecular Weight
506.5
MDL Number
MFCD06796890
PubChem ID
75627321
Melting Point
115-120 °C
Appearance
Yellow crystalline powder
Optical Rotation
[a]D20 = +10 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ng-(2,4-dinitrophenyl)-D-2,4-diaminobutyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the design of new pharmaceuticals, particularly in creating targeted therapies that require precise molecular structures for effective action.
  • Bioconjugation: This chemical is used in bioconjugation processes, where it helps to attach biomolecules to surfaces or other molecules, enhancing the functionality of drugs and diagnostics.
  • Analytical Chemistry: It aids in the development of analytical methods for detecting and quantifying specific biomolecules, which is essential in various research and clinical settings.
  • Research in Cancer Therapeutics: The compound is being explored for its potential applications in cancer treatment, particularly in the development of targeted delivery systems that improve drug efficacy while minimizing side effects.