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Catalog Number:
16171
CAS Number:
194471-85-7
Fmoc-cis-2-aminocyclohexanecarboxylic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-1,2-cis-ACHC-OH
Documents
$51.18 /250MG
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Product Information

Fmoc-cis-2-aminocyclohexanecarboxylic acid is a valuable building block in peptide synthesis, particularly favored for its ability to facilitate the introduction of cyclic structures into peptides. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely recognized for its stability during the synthesis process and ease of removal under mild conditions. Its unique cis configuration enhances the conformational flexibility of the resulting peptides, making it an excellent choice for researchers aiming to develop novel therapeutic agents or study protein interactions.

In practical applications, Fmoc-cis-2-aminocyclohexanecarboxylic acid is utilized in the design of bioactive peptides, which can be pivotal in drug discovery and development. Its ability to mimic natural amino acids while providing distinct structural features allows for the exploration of new biological activities. This compound is particularly relevant in the fields of medicinal chemistry and biochemistry, where the synthesis of complex peptide libraries is essential for advancing research and therapeutic innovations.

Synonyms
Fmoc-1,2-cis-ACHC-OH
CAS Number
194471-85-7
Purity
≥ 99% (HPLC)
Molecular Formula
C22H23NO4
Molecular Weight
365.4
MDL Number
MFCD02682625
PubChem ID
4139355
Melting Point
101-111?C
Appearance
White crystalline powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-1,2-cis-ACHC-OH
CAS Number
194471-85-7
Purity
≥ 99% (HPLC)
Molecular Formula
C22H23NO4
Molecular Weight
365.4
MDL Number
MFCD02682625
PubChem ID
4139355
Melting Point
101-111?C
Appearance
White crystalline powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-cis-2-aminocyclohexanecarboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the design of new pharmaceuticals, particularly in creating cyclic peptides that can enhance bioavailability and target specificity.
  • Bioconjugation: Researchers use it to facilitate the attachment of biomolecules, such as antibodies or enzymes, to therapeutic agents, improving the efficacy of drug delivery systems.
  • Material Science: In the development of novel materials, this compound can be used to create polymers with specific properties, including increased stability and enhanced mechanical strength.
  • Analytical Chemistry: It is employed as a standard in various analytical techniques, helping to calibrate instruments and validate methods for the analysis of complex mixtures.

Citations