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Catalog Number:
16101
CAS Number:
193693-67-3
Fmoc-D-nipecotic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Nip-OH, Fmoc-(R)-piperidine-3-carboxylic acid
Documents
$134.70 /1G
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Product Information

Fmoc-D-nipecotic acid is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of complex peptides. Its unique structure allows for efficient coupling reactions, making it an invaluable tool for researchers in medicinal chemistry and biochemistry.

In addition to its role in peptide synthesis, Fmoc-D-nipecotic acid has shown potential in the development of neuroprotective agents and in studies related to neurological disorders. Its ability to modulate neurotransmitter systems positions it as a candidate for further exploration in pharmacological applications. Researchers appreciate its stability and ease of use, which streamline the synthesis process and enhance overall yield. With its broad applicability in both academic and industrial settings, Fmoc-D-nipecotic acid stands out as a key reagent for advancing peptide-based therapeutics.

Synonyms
Fmoc-D-Nip-OH, Fmoc-(R)-piperidine-3-carboxylic acid
CAS Number
193693-67-3
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.41
MDL Number
MFCD04112683
PubChem ID
2756141
Melting Point
161 - 171 °C
Appearance
White powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Nip-OH, Fmoc-(R)-piperidine-3-carboxylic acid
CAS Number
193693-67-3
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.41
MDL Number
MFCD04112683
PubChem ID
2756141
Melting Point
161 - 171 °C
Appearance
White powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-nipecotic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. Its stability under various conditions makes it a preferred choice among chemists.
  • Drug Development: Researchers leverage its unique structure to design and develop new pharmaceuticals, particularly in the field of neuropharmacology, where it can influence neurotransmitter systems.
  • Bioconjugation: Fmoc-D-nipecotic acid is used in bioconjugation techniques to attach biomolecules to surfaces or other molecules, enhancing the functionality of drugs and diagnostic agents.
  • Material Science: The compound finds applications in creating advanced materials, such as polymers and nanomaterials, due to its ability to modify surface properties and improve adhesion.
  • Research in Neuroscience: Its structural similarity to neurotransmitters allows for studies on receptor interactions, aiding in the understanding of various neurological disorders and potential treatments.

Citations