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Catalog Number:
15723
CAS Number:
959578-11-1
Fmoc-L-2-amino-5-phenylpentanoic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Nva(5-phenyl)-OH, Fmoc-Nva(5-phenyl)-OH
Documents
$80.50 /250MG
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Product Information

Fmoc-L-2-amino-5-phenylpentanoic acid is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound, recognized for its protective Fmoc (9-fluorenylmethoxycarbonyl) group, facilitates the efficient assembly of peptides by providing a stable and easily removable protective group during solid-phase synthesis. Its unique structure, featuring a phenyl side chain, enhances the hydrophobic interactions within peptides, making it particularly valuable in the design of bioactive compounds and pharmaceuticals. Researchers appreciate its role in improving the solubility and stability of peptides, which is crucial for therapeutic applications.

In addition to its significance in peptide synthesis, Fmoc-L-2-amino-5-phenylpentanoic acid is also employed in the development of novel materials and bioconjugates. Its ability to form stable linkages with various biomolecules opens avenues for creating targeted drug delivery systems and diagnostic tools. The compound's compatibility with various coupling reagents and its ease of handling make it an essential choice for both academic and industrial laboratories focused on peptide chemistry and medicinal research.

Synonyms
Fmoc-L-Nva(5-phenyl)-OH, Fmoc-Nva(5-phenyl)-OH
CAS Number
959578-11-1
Purity
≥ 98% (HPLC)
Molecular Formula
C26H25NO4
Molecular Weight
415.49
MDL Number
MFCD06202350
PubChem ID
53398061
Appearance
White solid
Optical Rotation
[a]D20 = -10 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Nva(5-phenyl)-OH, Fmoc-Nva(5-phenyl)-OH
CAS Number
959578-11-1
Purity
≥ 98% (HPLC)
Molecular Formula
C26H25NO4
Molecular Weight
415.49
MDL Number
MFCD06202350
PubChem ID
53398061
Appearance
White solid
Optical Rotation
[a]D20 = -10 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-2-amino-5-phenylpentanoic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the design of peptide-based pharmaceuticals, particularly in creating more stable and effective drug candidates for various therapeutic areas.
  • Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of peptides to other biomolecules, which is essential for developing targeted therapies and diagnostics.
  • Research in Neuroscience: Its derivatives are explored in neuroscience research for their potential neuroprotective effects, contributing to the development of treatments for neurodegenerative diseases.
  • Material Science: The compound is also investigated in the field of material science for creating novel biomaterials that mimic natural tissues, enhancing applications in regenerative medicine.

Citations