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Catalog Number:
15690
CAS Number:
511272-41-6
Fmoc-(R)-3-amino-3-(3,5-dimethoxyphenyl)propionic acid
Purity:
≥ 99% (Chiral HPLC, HPLC)
Synonym(s):
Fmoc-D-β-Phe(3,5-dimethoxy)-OH, (R)-Fmoc-3,5-dimethoxy-β-phenylalanine
Documents
$127.79 /250MG
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Product Information

Fmoc-(R)-3-amino-3-(3,5-dimethoxyphenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of a 3,5-dimethoxyphenyl moiety, enhances its reactivity and compatibility with various coupling reagents, making it an ideal choice for researchers focused on developing complex peptide sequences.

In addition to its role in peptide synthesis, this compound has shown potential in drug development, particularly in the design of bioactive peptides with improved pharmacological properties. Its ability to facilitate the introduction of specific amino acid residues allows for the fine-tuning of peptide functionality, which is crucial in therapeutic applications. Researchers in the fields of biochemistry and pharmaceutical sciences will find Fmoc-(R)-3-amino-3-(3,5-dimethoxyphenyl)propionic acid to be an invaluable tool in their quest for innovative solutions.

Synonyms
Fmoc-D-β-Phe(3,5-dimethoxy)-OH, (R)-Fmoc-3,5-dimethoxy-β-phenylalanine
CAS Number
511272-41-6
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C26H25NO6
Molecular Weight
447.49
MDL Number
MFCD03428022
PubChem ID
22309351
Melting Point
178 - 182 ºC (Lit.)
Appearance
White powder
Optical Rotation
[a]D20 = 25 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-β-Phe(3,5-dimethoxy)-OH, (R)-Fmoc-3,5-dimethoxy-β-phenylalanine
CAS Number
511272-41-6
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C26H25NO6
Molecular Weight
447.49
MDL Number
MFCD03428022
PubChem ID
22309351
Melting Point
178 - 182 ºC (Lit.)
Appearance
White powder
Optical Rotation
[a]D20 = 25 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(3,5-dimethoxyphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the efficient assembly of complex peptides while preventing unwanted reactions.
  • Drug Development: Its unique structure can be leveraged in the design of new pharmaceuticals, particularly in creating compounds with enhanced bioactivity and selectivity for specific targets.
  • Bioconjugation: The chemical is useful in bioconjugation techniques, where it can be attached to biomolecules, aiding in the development of targeted drug delivery systems.
  • Research in Neuroscience: Its derivatives are being explored for their potential in modulating neurotransmitter systems, which can lead to advancements in treatments for neurological disorders.
  • Material Science: The compound can be incorporated into polymer matrices for creating smart materials, which respond to environmental stimuli, enhancing their application in various fields such as sensors and actuators.

Citations