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Catalog Number:
15588
CAS Number:
507472-21-1
Fmoc-(S)-3-amino-3-(4-trifluoromethylphenyl)propionic acid
Purity:
≥ 98% (NMR)
Synonym(s):
Fmoc-L-β-Phe(4-CF3)-OH, (S)-Fmoc-4-trifluoromethyl-β-phenylalanine
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$66.80 /100MG
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Product Information

Fmoc-(S)-3-amino-3-(4-trifluoromethylphenyl)propionic acid is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique trifluoromethylphenyl side chain enhances the compound's hydrophobicity and stability, making it particularly valuable in the design of bioactive peptides and pharmaceuticals. Researchers appreciate its role in facilitating the synthesis of complex peptide structures, which can lead to the development of novel therapeutics.

In addition to its applications in peptide synthesis, Fmoc-(S)-3-amino-3-(4-trifluoromethylphenyl)propionic acid is also explored in the fields of material science and biochemistry. Its ability to form stable interactions with various biomolecules opens avenues for research in drug delivery systems and biomolecular engineering. With its unique properties and practical applications, this compound stands out as a crucial tool for researchers and industry professionals aiming to innovate in peptide chemistry and related fields.

Synonyms
Fmoc-L-β-Phe(4-CF3)-OH, (S)-Fmoc-4-trifluoromethyl-β-phenylalanine
CAS Number
507472-21-1
Purity
≥ 98% (NMR)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD03428003
PubChem ID
2759206
Melting Point
188 - 193 ?C (Lit.)
Appearance
White solid
Optical Rotation
[a]D25 = -17 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-Phe(4-CF3)-OH, (S)-Fmoc-4-trifluoromethyl-β-phenylalanine
CAS Number
507472-21-1
Purity
≥ 98% (NMR)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD03428003
PubChem ID
2759206
Melting Point
188 - 193 ?C (Lit.)
Appearance
White solid
Optical Rotation
[a]D25 = -17 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(4-trifluoromethylphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing researchers to create complex peptide structures efficiently.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, especially those targeting specific protein interactions, enhancing therapeutic efficacy.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.
  • Research in Neuroscience: This compound is instrumental in studying neurotransmitter systems and receptor interactions, aiding in the understanding of neurological disorders and potential treatments.
  • Fluorinated Compound Applications: Its trifluoromethyl group enhances lipophilicity, making it beneficial in designing compounds with improved bioavailability and metabolic stability in various applications.

Citations