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Catalog Number:
15554
CAS Number:
507472-15-3
Fmoc-(S-3-amino-3-(2-chlorophenyl)propionic acid
Synonym(s):
Fmoc-L-β-Phe(2-Cl)-OH, (S-Fmoc-2-chloro-β-phenylalanine
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Product Information

Fmoc-(S)-3-amino-3-(2-chlorophenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective protection of amino groups during the synthesis of peptides, enhancing the efficiency and yield of the desired products. Its specific chirality and the presence of a chlorophenyl group contribute to its effectiveness in creating complex peptide structures, making it invaluable in pharmaceutical research and development.

Researchers and industry professionals appreciate this compound for its ability to improve the solubility and stability of peptides, which is critical in the formulation of therapeutic agents. Its applications extend to the synthesis of bioactive peptides, where it serves as a key intermediate in the production of compounds with potential applications in drug discovery and development. The unique properties of Fmoc-(S)-3-amino-3-(2-chlorophenyl)propionic acid position it as a preferred choice for chemists seeking reliable and efficient solutions in peptide synthesis.

Synonyms
Fmoc-L-β-Phe(2-Cl)-OH, (S-Fmoc-2-chloro-β-phenylalanine
CAS Number
507472-15-3
Molecular Formula
C24H20ClNO4
Molecular Weight
421.88
MDL Number
MFCD03427996
PubChem ID
22831635
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-β-Phe(2-Cl)-OH, (S-Fmoc-2-chloro-β-phenylalanine
CAS Number
507472-15-3
Molecular Formula
C24H20ClNO4
Molecular Weight
421.88
MDL Number
MFCD03427996
PubChem ID
22831635
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(2-chlorophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It is used in the development of pharmaceutical compounds, especially in designing inhibitors or modulators that target specific biological pathways, benefiting the pharmaceutical industry.
  • Bioconjugation: The compound can be employed in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the efficacy of drug delivery systems.
  • Research in Neuroscience: Its derivatives are often explored in neuroscience research for their potential role in modulating neurotransmitter systems, aiding in the understanding of neurological disorders.
  • Analytical Chemistry: The compound is utilized in analytical methods to study protein interactions and conformational changes, providing valuable insights in biochemical research.

Citations