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Catalog Number:
15528
CAS Number:
332064-94-5
Fmoc-D-β-homopropargylglycine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-β-HomoPra-OH, Fmoc-(R)-3-amino-5-hexynoic acid
Documents
$79.22 /25MG
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Product Information

Fmoc-D-b-homopropargylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a unique propargyl group, which enhances its reactivity and allows for the incorporation of various functional groups through click chemistry. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group provides stability during synthesis, making it an ideal choice for researchers focused on developing complex peptides and biologically active compounds.

In practical applications, Fmoc-D-b-homopropargylglycine is particularly valuable in the design of peptide-based therapeutics and in the study of protein interactions. Its ability to facilitate the formation of diverse peptide libraries enables researchers to explore new drug candidates and optimize existing ones. Additionally, the compound's unique structure allows for the introduction of bioorthogonal reactions, which are essential for targeted drug delivery systems. With its robust properties and significant potential in pharmaceutical research, Fmoc-D-b-homopropargylglycine stands out as a crucial tool for advancing peptide chemistry.

Synonyms
Fmoc-D-β-HomoPra-OH, Fmoc-(R)-3-amino-5-hexynoic acid
CAS Number
332064-94-5
Purity
≥ 98% (HPLC)
Molecular Formula
C21H19NO4
Molecular Weight
349.39
MDL Number
MFCD01860910
PubChem ID
53398008
Melting Point
150 - 156 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -21 ± 2º (C=1, in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-β-HomoPra-OH, Fmoc-(R)-3-amino-5-hexynoic acid
CAS Number
332064-94-5
Purity
≥ 98% (HPLC)
Molecular Formula
C21H19NO4
Molecular Weight
349.39
MDL Number
MFCD01860910
PubChem ID
53398008
Melting Point
150 - 156 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -21 ± 2º (C=1, in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-b-homopropargylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of unique functionalities into peptide chains.
  • Drug Development: Its structural properties make it valuable in the design of novel therapeutic agents, especially in the development of inhibitors or modulators for various biological targets.
  • Bioconjugation: The alkyne group in this compound facilitates click chemistry, enabling researchers to efficiently attach biomolecules for applications in drug delivery and diagnostics.
  • Research in Neuroscience: It is used in the study of neuropeptides, providing insights into signaling pathways and potential treatments for neurological disorders.
  • Material Science: This compound can be utilized in the development of functional materials, such as hydrogels, which have applications in tissue engineering and regenerative medicine.

Citations