Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
15454
CAS Number:
479064-99-8
Fmoc-(S)-3-amino-3-(4-methylphenyl)propionic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-β-Phe(4-Me)-OH, (S)-Fmoc-4-methyl-β-phenylalanine
Documents
$50.30 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-(S)-3-amino-3-(4-methylphenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and pharmaceutical research. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for the introduction of a 4-methylphenyl side chain, enhancing the compound's hydrophobic properties, making it particularly valuable in the development of bioactive peptides. Researchers appreciate its stability and ease of use, which facilitate streamlined synthesis processes.

In practical applications, Fmoc-(S)-3-amino-3-(4-methylphenyl)propionic acid is employed in the design of peptide-based drugs and therapeutic agents, particularly in the fields of oncology and neurology. Its ability to improve peptide solubility and bioavailability makes it a preferred choice for scientists aiming to create more effective drug candidates. Additionally, this compound's compatibility with various coupling reagents and its favorable reaction kinetics further underscore its significance in peptide chemistry, making it an indispensable tool for researchers and industry professionals alike.

Synonyms
Fmoc-L-β-Phe(4-Me)-OH, (S)-Fmoc-4-methyl-β-phenylalanine
CAS Number
479064-99-8
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD03427973
PubChem ID
2759200
Melting Point
188 - 190 °C
Appearance
White powder
Optical Rotation
[a]D25 = -34 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-Phe(4-Me)-OH, (S)-Fmoc-4-methyl-β-phenylalanine
CAS Number
479064-99-8
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD03427973
PubChem ID
2759200
Melting Point
188 - 190 °C
Appearance
White powder
Optical Rotation
[a]D25 = -34 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(4-methylphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective attachment of amino acids. Its stability under various conditions makes it a preferred choice for researchers aiming to create complex peptides.
  • Drug Development: In pharmaceutical research, it is used to develop and optimize peptide-based drugs, particularly those targeting specific receptors. Its unique structure can enhance the bioactivity of therapeutic peptides.
  • Bioconjugation: This chemical is valuable in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, improving the efficacy of diagnostics and therapeutics in the biomedical field.
  • Research in Neuroscience: Its application in synthesizing neuropeptides allows researchers to explore neurological pathways and develop potential treatments for neurological disorders.
  • Material Science: The compound can be utilized in creating functionalized materials, enhancing the properties of polymers and nanomaterials for various industrial applications.

Citations