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Catalog Number:
15444
CAS Number:
479064-89-6
Fmoc-(S-3-amino-3-(4-fluorophenyl)propionic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-β-Phe(4-F)-OH, (S-Fmoc-4-fluoro-β-phenylalanine
Documents
$72.31 /250MG
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Product Information

Fmoc-(S)-3-amino-3-(4-fluorophenyl)propionic acid is a valuable compound widely utilized in peptide synthesis and medicinal chemistry. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of a 4-fluorophenyl group, enhances its utility in the development of bioactive peptides and pharmaceuticals. Researchers appreciate its role in facilitating the synthesis of complex peptide sequences, allowing for the exploration of new therapeutic agents with improved efficacy and specificity.

This compound is particularly relevant in the fields of drug discovery and development, where it serves as a building block for the creation of peptide-based drugs. Its stability and reactivity make it an ideal candidate for various coupling reactions, streamlining the synthesis process. Additionally, the incorporation of fluorinated aromatic groups can enhance the pharmacological properties of the resulting peptides, making them more potent and selective. Overall, Fmoc-(S)-3-amino-3-(4-fluorophenyl)propionic acid is an essential tool for researchers aiming to innovate in peptide chemistry and drug design.

Synonyms
Fmoc-L-β-Phe(4-F)-OH, (S-Fmoc-4-fluoro-β-phenylalanine
CAS Number
479064-89-6
Purity
≥ 98% (HPLC)
Molecular Formula
C24H20FNO4
Molecular Weight
405.42
MDL Number
MFCD03427995
PubChem ID
2759194
Appearance
White to off-white solid
Optical Rotation
[a]D25 = -23.0 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-β-Phe(4-F)-OH, (S-Fmoc-4-fluoro-β-phenylalanine
CAS Number
479064-89-6
Purity
≥ 98% (HPLC)
Molecular Formula
C24H20FNO4
Molecular Weight
405.42
MDL Number
MFCD03427995
PubChem ID
2759194
Appearance
White to off-white solid
Optical Rotation
[a]D25 = -23.0 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(4-fluorophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active compounds. Its protective Fmoc group allows for selective deprotection, facilitating the formation of complex peptide structures.
  • Drug Development: In medicinal chemistry, it is used to create novel drug candidates that target specific biological pathways. The incorporation of the fluorophenyl group can enhance the compound's bioactivity and selectivity, making it a valuable tool in drug discovery.
  • Bioconjugation: This chemical is effective in bioconjugation processes, where it can be linked to biomolecules such as proteins or antibodies. This application is crucial in developing targeted therapies and diagnostic agents in the biopharmaceutical industry.
  • Research in Neuroscience: Its structural properties make it a candidate for studying neurotransmitter systems and developing neuroactive compounds. Researchers can explore its effects on synaptic transmission and neuroprotection.
  • Analytical Chemistry: The compound can also be utilized in analytical techniques to assess the purity and composition of peptide-based drugs. Its unique structure aids in the identification and quantification of related compounds in complex mixtures.

Citations