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Catalog Number:
15365
CAS Number:
270063-53-1
3,4-Difluoro-L-β-homophenylalanine hydrochloride
Purity:
≥ 98%
Synonym(s):
L-β-HomoPhe(3,4-DiF)-OH·HCl, (S)-3-Amino-4-(3,4-difluorophenyl)butyric acid hydrochloride
Documents
$100.05 /25MG
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Product Information

3,4-Difluoro-L-b-homophenylalanine hydrochloride is a specialized amino acid derivative that has gained attention in pharmaceutical research and development. This compound is recognized for its unique fluorinated structure, which enhances its stability and bioactivity compared to non-fluorinated analogs. Its application is particularly significant in the design of novel peptides and proteins, where it can be utilized to modulate biological activity, improve pharmacokinetic properties, and enhance binding affinity in drug discovery processes. Researchers have found that incorporating 3,4-Difluoro-L-b-homophenylalanine into peptide sequences can lead to improved therapeutic profiles, making it a valuable tool in medicinal chemistry.

In addition to its role in drug development, this compound has potential applications in the field of biochemistry and molecular biology, particularly in studies involving protein folding and function. Its unique properties allow for the exploration of new pathways in enzyme activity and receptor interactions, providing researchers with innovative avenues for investigation. The ability to modify peptide structures with 3,4-Difluoro-L-b-homophenylalanine opens up possibilities for creating targeted therapies and enhancing the efficacy of existing treatments.

Synonyms
L-β-HomoPhe(3,4-DiF)-OH·HCl, (S)-3-Amino-4-(3,4-difluorophenyl)butyric acid hydrochloride
CAS Number
270063-53-1
Purity
≥ 98%
Molecular Formula
C10H11F2NO2·HCl
Molecular Weight
251.66
MDL Number
MFCD01861049
Melting Point
182 - 188 ?C
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -18.2 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
L-β-HomoPhe(3,4-DiF)-OH·HCl, (S)-3-Amino-4-(3,4-difluorophenyl)butyric acid hydrochloride
CAS Number
270063-53-1
Purity
≥ 98%
Molecular Formula
C10H11F2NO2·HCl
Molecular Weight
251.66
MDL Number
MFCD01861049
Melting Point
182 - 188 ?C
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -18.2 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3,4-Difluoro-L-b-homophenylalanine hydrochloride is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a valuable building block in the synthesis of novel pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Protein Engineering: It is used in the design of modified proteins, allowing researchers to study the effects of fluorinated amino acids on protein structure and function.
  • Biochemical Research: The compound aids in investigating enzyme activity and metabolic pathways, providing insights into biochemical processes that could lead to new therapeutic strategies.
  • Drug Design: Its unique properties make it a candidate for creating fluorinated analogs of existing drugs, potentially improving their efficacy and selectivity.
  • Material Science: This chemical is explored in the development of advanced materials, particularly in coatings and polymers that require enhanced chemical resistance.

Citations